“…It is used for the treatment of hepatic encephalopathy, traveler's diarrhea, irritable bowel syndrome, Clostridium difficile infections, ulcerative colitis and acute diarrhea [ 5 ].Rifaximin has the phenomenon of polymorphism. It has five known polymorphs (pseudo) α, β, γ, δ and ε [ 1 , 6 ]. The crystalline form having a minimal systemic absorption, is α form.…”