Serendipitous discovery of a novel polymorph of an immunosuppressant drug azathioprine: phase transformation, solubility, dissolution and stability study

Abstract

A novel polymorph of an immunosuppressant drug azathioprine (AZP) is prepared (F-III) along with two solvates (2-methoxyethanol (MEE) and 1,4-Dioxane (DOX)) and a monohydrate of AZP. The crystal structures were...