Highly Oxygenated Monoterpenes from Chenopodium ambrosioides

Abstract

Three new monoterpenes (3-5) were isolated from an organic extract of the aerial parts of Chenopodium ambrosioides. Structures were established on the basis of MS and NMR spectroscopic ((1)H, (13)C, (1)H-(1)H COSY, HMQC and HMBC) data.

A New Kaempferol Glycoside with Antioxidant Activity from Chenopodium ambrosioides Growing in Egypt

“…Fractions (250 ml each) were collected, concentrated and examined (PC, S 1 &S 2 , 5% AlCl 3 and 1% FeCl 3 , UV light for detection). Similar fractions were pooled according to their pattern upon paper chromatography, to afford five main fractions (1)(2)(3)(4)(5) …”

“…The genus Chenopodium constituted of approximately 120 species, 45 of which are known to be distributed all over the world, and nine of which are distributed in Egypt 1,2 . Different species belonging to this genus showed numerous pharmacological properties 3,4 .…”

“…Reviewing the literature revealed that the different parts of C. ambrosioides showed numerous biological activities i.e., antimicrobial 16,17 , cytotoxicity 18 , antioxidant 19 , larvicidal 20 , antidiabetic 4 , antiparasitic 21 , antiviral 22 , and molluscidal 23 . Moreover, from the phytochemistry point of view C. ambrosioides is known to contain secondary metabolites i.e., saponins 24 , terpenoids 2,25,26 , flavonol glycosides 27,28 , flavone glycosides 29 , and chenopodiumamines & chenopodiumoside 30 . The accumulation of the reactive free radicals in our bodies led to phenomena known as oxidative stress which represent the imbalance between the endogenous antioxidant molecules in our bodies and the extent of such species.…”

Chemical composition and antimicrobial activity of crude, aqueous, ethanol extracts and essential oils ofDysphania ambrosioides(L.) Mosyakin & Clemants

“…The composition of the essential oil of D. ambrosioides has been the subject of several studies. Although original studies of the oil date back to 1854, many constituents were identified as ascaridol, limonene, α-terpinene and p-cymene (Cavalli et al, 2004;Ahmed, 2000). Other chemical composition has been described by Lawrence (1999) for Eos of D. ambrosioides, the major components being in various origins: ascaridole, pinocarvone, terpinene 4-yle acetate, limonene, α-terpinene, α-phellandrene, p-cymene (Cavalli, 2002;Jonhson & Croteau, 1984).…”

Activity of the Essential Oil from <i>Chenopodium ambrosioides</i> Grown in Cuba against <i>Leishmania amazonensis</i>

“…The importance of Chenopodium species is due to their wide variety of medicinal properties. Chemical investigations on some members of this genus concerned essential oils, sesquiterpenes, ecdysteroids, fl avonoids and saponins [7] .…”