Highly integrated oral drug delivery system with valve based on Electro-Active-Polymer

Goettsche, T.; Schumacher, Axel; Kohnle, J.; Messner, S.; Zengerle, Roland

doi:10.1109/memsys.2007.4433071

Cited by 4 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The space between the CP electrodes was filled with a SPE. Bulk expansion Microfluidic valve, [29] rotating balloon seal for bifurcation stenting, [44] mechanotransduction chip. [30] Linear (liquid) Refreshable braille display, [45] actuating textiles, [46] meshes, [47] and yarns.…”

Section: Configurationsmentioning

confidence: 99%

“…[50] Bilayer (liquid) Variable-camber propeller on aquatic foil, [51] micro-actuator hinges, [52] including rigid elements, [53] multiple actuators and sensors, [54,55] micro-anastomosis connector. [56] Buckling Microfluidic valve, [44,57] drug delivery. [58] Trilayer (liquid) Peristaltic pump.…”

Section: Configurationsmentioning

confidence: 99%

“…[118] This wide variety of fabrication methods open the way to attach the CP microactuators to other elements and different electronic, optical, and micromechanical devices on positionable platforms and thus develop new scientific instruments. It resulted in an assortment of devices comprising CP microactuators: moving pixels, [119] perpendicular, in-plane actuation, [120] valves for microfluidics either using moving plates [57] or a buckling membrane [44,58] and drug delivery devices. [121] Since these bilayer microactuators require a liquid electrolyte, applications towards cell biology, where the cell culture medium can be used as the operating electrolyte, are particularly interesting and several applications for cell biology and BioMEMS that use CP actuators have been demonstrated.…”

Section: Microfabricated Conjugated Polymer Actuators Were First Demo...mentioning

confidence: 99%

“…[30,31] A microvalve for an intra-oral drug delivery was developed by HSG-IMIT, Germany, and Micromuscle AB, Sweden. [44,58] Their valve employed the buckling movement of a PPy membrane to open and close the microfluidic channel and thus control the release of the drug.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Conjugated Polymer Actuators and Devices: Progress and Opportunities

2019

View full text Add to dashboard Cite

Conjugated polymers (CP), as exemplified by polypyrrole (PPy), are intrinsically conducting polymers with potential for development as soft actuators or 'artificial muscles' for numerous applications. Significant progress has been made in our understanding of these materials and the actuation mechanisms, aided by the development of physical and electrochemical models. Current research is focused on developing applications utilizing the advantages that CP actuators have (e.g. low driving potential, easy to miniaturise) over other actuating materials and on developing ways of overcoming their inherent limitations. CP actuators are available as films, filaments/yarns and textiles, operating in liquids as well as in air for, ready for use by engineers. This review initially highlights the milestones made in understanding these unique materials and their development as actuators. The primary focus is on the recent progress, developments, applications, and future opportunities for improvement and exploitation of these materials possessing a wealth of multifunctional properties.Received: ((will be filled in by the editorial staff))Revised: ((will be filled in by the editorial staff))

show abstract

Section: Configurationsmentioning

confidence: 99%

Section: Configurationsmentioning

confidence: 99%

Section: Microfabricated Conjugated Polymer Actuators Were First Demo...mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Conjugated Polymer Actuators and Devices: Progress and Opportunities

2019

View full text Add to dashboard Cite

show abstract

“…Being a polymer, PPy is intrinsically light-weight (about 1.5 g cm −3 [48]), thus easing the task of achieving quasi-neutral buoyancy of the whole microrobot. Moreover, it has low power consumption and, importantly, low operating voltages (1-2 V), so that it could be driven by an onboard power-supply [49]. PPy can be operated in almost any electrolyte, and has been shown to be biocompatible [50].…”

Section: Short Overview Of Suitable Actuation Technologiesmentioning

confidence: 99%

Propulsion of swimming microrobots inspired bymetachronal wavesin ciliates: from biology to material specifications

et al. 2013

View full text Add to dashboard Cite

Abstract. The quest for swimming microrobots originates from possible applications in medicine, especially involving navigation in bodily fluids. Swimming microorganisms have become a source of inspiration because their propulsion mechanisms are effective in the low-Reynolds number regime. In this study, we address a propulsion mechanism inspired by metachronal waves, i.e. the spontaneous coordination of cilia leading to the fast swimming of ciliates. We analyze the biological mechanism (referring to its particular embodiment in Paramecium caudatum), and we investigate the contribution of its main features to the swimming performance, through a three-dimensional finiteelements (FE) model, in order to develop a simplified, yet effective artificial design. We propose a bioinspired propulsion mechanism for a swimming microrobot based on a continuous cylindrical electroactive surface exhibiting perpendicular wave deformations travelling longitudinally along its main axis. The simplified propulsion mechanism is conceived specifically for microrobots that embed a micro-actuation system capable of executing the bioinspired propulsion (self-propelled microrobots). Among the available electroactive polymers (EAPs), we select Polypyrrole (PPy) as the possible actuation material and we assess it for this particular embodiment. The results are used to appoint target performance specifications for the development of improved or new electroactive materials to attain metachronal-waves-like propulsion.Propulsion of swimming microrobots inspired by metachronal waves 2

show abstract