“…FET based biosensors have gained much interest because of their practical advantages, such as high sensitivity, quick response time, portability, cheap cost, and simplicity of use for directly detecting analytes in biological fluids without any preprocessing of samples. , The FET device can be used in POC biosensing applications and offers the benefits of batch production and simple integration with readout circuits. , The analyte interaction in FETs occurs at the device channel surface, which is connected to the source and drain terminals. − This interaction of the analyte with the channel surface results in the transfer of charges, which ultimately causes a change in the output current of the device. , In FET-based biosensing devices, usually materials like graphene, carbon nanotube, metal oxide, and transition metal dichalcogenides (TMDs), and semiconducting polymers like poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT/PSS), P3HT, and polyaniline (PANI) are used for the channel layer. − 2D TMD-based semiconductor material for FET biosensors surpasses traditional semiconductors with advantages like large surface area, chemical stability, and high conductivity. They offer low detection limits, flexibility, and real-time monitoring, making them promising for diverse biosensing applications. − In the different available TMD materials, we particularly choose MoSe 2 as a transistor channel layer.…”