Higher adenoma detection rate with the endocuff: a randomized trial

Abstract

Different techniques have been introduced to improve the endoscopist's view and enhance the detection of polyps. The endocuff is a polymer sleeve cap that is connected to the tip of the colonoscope in order to improve visualization of the mucosa during colonoscopy. The aim of the study was to compare adenoma detection rates (ADR) of endocuff-assisted colonoscopy and conventional colonoscopy. Patients 50 years or older were randomized into two groups: an endocuff-assisted colonoscopy group and a conventional colonoscopy group without the endocuff. A total of 337 patients were included: 174 in the endocuff group and 163 in the conventional group. The median age was 61 years (interquartile range 55 - 70 years), and 74 % were women. The ADR was higher in the endocuff group than in the conventional group (22.4 % vs. 13.5 %; = 0.02). The mean number of adenomas was 0.30 (SD 0.25) in the endocuff group and 0.21 (SD 0.26) in the conventional group ( = 0.02). The rate of ileal intubation was lower in the endocuff group (73 % vs. 87 %; < 0.001). No serious adverse events occurred with the use of the endocuff. Endocuff colonoscopy achieved a greater ADR than conventional colonoscopy.Trial registered at ClinicalTrials.gov (NTC02387593).

EndoCuff‐assisted colonoscopy could improve adenoma detection rate: A meta‐analysis of randomized controlled trials

“…Four studies reported advanced adenoma detection rate. At least one advanced adenoma was detected in 14.7% of patients in the EAC group and 15.2% in the SC group.…”

“…Four studies evaluated cecal intubation time between two groups. The mean cecal intubation time ranged 4.05–10.0 minutes in the EAC group and 4.1–12.0 minutes in the SC group.…”

Randomized control trial of adenoma detection rate in Endocuff‐assisted colonoscopy versus transparent hood‐assisted colonoscopy

“…High‐definition colonoscopes aid in detection and are now widely considered fundamental to detection and effective treatments . Adjunctive devices and techniques have also been widely investigated, including chromoendoscopy and image‐enhanced endoscopy; mucosal exposure devices such as transparent hood, Endocuff, EndoRings,and the Third Eye Retroscope; and ultra‐wide‐angle endoscopes such as full‐spectrum endoscopy and the extra‐wide‐view colonoscope …”

“…The Endocuff, which is a flexible cap with two circle rows of plastic, hinged soft wings, has been developed to improve the ADR compared with SC . It flattens the mucosal folds during withdrawal and keeps the tip of the colonoscope steady during interventions.…”

“…6 High-definition colonoscopes aid in detection and are now widely considered fundamental to detection and effective treatments. 7 Adjunctive devices and techniques have also been widely investigated, including chromoendoscopy [8][9][10] and image-enhanced endoscopy [11][12][13] ; mucosal exposure devices such as transparent hood, [12][13][14][15][16][17][18] Endocuff, [19][20][21][22][23][24][25][26][27][28][29][30][31] EndoRings, 6,32 and the Third Eye Retroscope 33 ; and ultra-wide-angle endoscopes such as full-spectrum endoscopy 6,34 and the extra-wide-view colonoscope. 35,36 A transparent hood attached to the distal tip of the colonoscope has been reported to improve the cecal intubation rate and adenoma detection rate (ADR) compared with standard colonoscopy (SC).…”