High-throughput colorimetric assays for mercury(<scp>ii</scp>) in blood and wastewater based on the mercury-stimulated catalytic activity of small silver nanoparticles in a temperature-switchable gelatin matrix

Sun, Zongzhao; Zhang, Ning; Si, Yanmei; Li, Shuai; Wen, Jiangwei; Zhu, Xiangbing; Wang, Hua

doi:10.1039/c4cc03851g

Cited by 82 publications

(40 citation statements)

References 21 publications

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“…The welldispersed lignin−AgNP complex solution with a concentration of 0.02 mg/mL was prepared, and different volumes (0, 50, 100, 150, 200, 250, 300, 350, 400, 450, and 500 μL) of Hg 2+ (HgCl 2 , 10 −3 mol/L) were added into 3 mL of lignin−AgNP solution. By contrast, 500 μL of many kinds of metal ions solutions (NaCl, KCl, CaCl 2 , Al(NO 3 2.5. Characterization of AgNPs and Lignin.…”

Section: Selective and Sensitivementioning

confidence: 99%

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺

Shen

Luo

Wang

et al. 2014

ACS Appl. Mater. Interfaces

116

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This study reports the rapid preparation of silver nanoparticles (AgNPs) from Tollens' reagent under microwave irradiation. In the synthesis, lignin with reducing groups and spatial three-dimensional structure was used as reducing and stabilizing agents without other chemical reagents, and the effects of the ratio of lignin to Ag(+), reaction temperature, and heating time on the synthesis of AgNPs were investigated. The obtained AgNPs were further characterized by UV-vis, Malvern particle size, TEM, XRD, and XPS analyses. The structural changes of lignin before and after reaction were also studied by FT-IR, (1)H NMR, (13)C NMR, and GC-MS. The results revealed that the obtained AgNPs were mostly spherical with diameters of around 24 nm. The optimum reaction conditions were a ratio 50 mg of lignin to 0.3 mM of Ag(+), a microwave irradiation temperature of 60 °C, and a heating time of 10 min. Moreover, AgNPs redispersed well in water and ethanol after centrifugation for the removal of lignin. During the formation of AgNPs, lignin was oxidized, and the side chains of lignin were partly disrupted into small molecules, such as hydrocarbon and alcohol. The resultant lignin-AgNPs showed highly selective sensing detection for Hg(2+), and the color of the lignin-AgNP solution containing Hg(2+) decreased gradually with increasing amounts of Hg(2+) within seconds, but the other 19 metal ions had little effect on the color and surface plasmon absorption band of the lignin-AgNPs. Also, there was a linear relationship between the absorbance and Hg(2+) concentration, with a limit of detection concentration of 23 nM. This study provides not only a new way to take advantage of agricultural and forestry residues, but also a green and rapid method for the synthesis of AgNPs to detect the toxic ion Hg(2+) selectively and sensitively.

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Section: Selective and Sensitivementioning

confidence: 99%

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺

Shen

Luo

Wang

et al. 2014

ACS Appl. Mater. Interfaces

116

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“…9, 10 A variety of nanomaterials have been employed as colorimetric probes because of their unique physical and chemical properties. 11 Among those colorimetric probes, noble metal nanomaterials, especially gold nanoparticles (NPs), have been extensively used in nanoparticle aggregation-based colorimetric assays due to their high extinction coefficients and distance-dependent optical properties. 12, 13 However, gold NPs as colorimetric probes have to be confronted with some limitations for their wide application especially in resource-limited settings because of their intrinsic high cost.…”

Section: Introductionmentioning

confidence: 99%

Cost-effective and sensitive colorimetric immunosensing using an iron oxide-to-Prussian blue nanoparticle conversion strategy

Sanjay

2016

Analyst

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The development of new sensitive, cost-effective and user-friendly colorimetric bioassays is in increasing demand to meet the requirement of modern clinical diagnostics and field detection. Herein, a novel iron oxide-to-Prussian blue (PB) nanoparticles (NPs) conversion strategy was developed and applied to sensitive colorimetric immunosensing of cancer biomarkers. In a typical sandwich-type immunosensing system, the captured spherical antibody-conjugated iron oxide NPs were transformed into cubic PB NPs, which exhibited highly visible blue color with high molar extinction coefficients. Hence, a new colorimetric immunosensing strategy was developed as a result of this low cost and simple transformation process. Without the aid of any complex nanoparticle stabilizing ligands and signal amplification process, prostate-specific antigen as a model analyte can be detected at a concentration as low as 1.0 ng·mL−1 by the naked eye with good reliability for detection of real human serum samples. This is the first attempt to develop and apply the iron oxide-to-PB NPs colorimetric conversion strategy for immunosensing, and shows great promise for the development of new sensitive, cost-effective and user-friendly colorimetric bioassays in various bioanalytical applications, especially in low-resource settings.

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“…In 2014, Wang and co-workers found that small AgNPs showed relatively low catalytic activity in the 3,3,5,5-tetramethylbenzidine (TMB)À H 2 O 2 reaction at a low concentration. [26] However, when Hg 2 + ions were added into the reaction system, the catalytic activity could be significantly enhanced, which resulted in a visible deep blue reaction product. Based on the specific mercury-stimulated catalytic activity of AgNPs, they developed a colorimetric strategy for detecting Hg 2 + ions ( Figure 1D).…”

Section: Noble Metal Nanoparticles With Catalytic Behaviormentioning

confidence: 99%

“…D) Hg 2 + ion detection assay based on Ag nanoparticles. [26] Reproduced from ref. [26] with permission; copyright: 2014, Royal Society of Chemistry.…”

Section: Noble Metal Nanoparticles With Catalytic Behaviormentioning

confidence: 99%

Enzyme Mimic Nanomaterials and Their Biomedical Applications

et al. 2020

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Nanomaterials with enzyme‐mimicking behavior (nanozymes) have attracted a lot of research interest recently. In comparison to natural enzymes, nanozymes hold many advantages, such as good stability, ease of production and surface functionalization. As the catalytic mechanism of nanozymes is gradually revealed, the application fields of nanozymes are also broadly explored. Beyond traditional colorimetric detection assays, nanozymes have been found to hold great potential in a variety of biomedical fields, such as tumor theranostics, antibacterial, antioxidation and bioorthogonal reactions. In this review, we summarize nanozymes consisting of different nanomaterials. In addition, we focus on the catalytic performance of nanozymes in biomedical applications. The prospects and challenges in the practical use of nanozymes are discussed at the end of this Minireview.

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High-throughput colorimetric assays for mercury(ii) in blood and wastewater based on the mercury-stimulated catalytic activity of small silver nanoparticles in a temperature-switchable gelatin matrix

Cited by 82 publications

References 21 publications

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺

Cost-effective and sensitive colorimetric immunosensing using an iron oxide-to-Prussian blue nanoparticle conversion strategy

Enzyme Mimic Nanomaterials and Their Biomedical Applications

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High-throughput colorimetric assays for mercury(ii) in blood and wastewater based on the mercury-stimulated catalytic activity of small silver nanoparticles in a temperature-switchable gelatin matrix

Cited by 82 publications

References 21 publications

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg2+

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg2+

Cost-effective and sensitive colorimetric immunosensing using an iron oxide-to-Prussian blue nanoparticle conversion strategy

Enzyme Mimic Nanomaterials and Their Biomedical Applications

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High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺

High-Value Utilization of Lignin to Synthesize Ag Nanoparticles with Detection Capacity For Hg²⁺