High-speed spectral domain polarization- sensitive optical coherence tomography using a single camera and an optical switch at 1.3  µm

Lee, Sang-Won; Jeong, Hyun Chul; Kim, Beop Min

doi:10.1117/1.3277668

Cited by 48 publications

(20 citation statements)

References 15 publications

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“…The combined bandwidth produced was 145 nm centered at 1330 nm, having an output power of 10 mW and a coherence length of 5.4 m. Other novel tandem-SLD sources are the BroadLighter D-890 (2 SLDs), Q-940, and Q-1350 (4 SLDs) with bandwidth of 150 nm, 300 nm, and 280 nm, respectively [19], resulting in coherence lengths of 2.3 μm, 1.3 μm, and 2.9 μm, respectively. An example of a quantum-well double SLD was the DenseLight DL-BD9-CS31159A, a 25-mW SLD with a bandwidth of 170 nm at 1310 nm, and with the L C of 4.4 μm [30]. All of these SLDs can be generated by this model to investigate their A-scans.…”

Section: Tandem Sldsmentioning

confidence: 99%

Modeling of low coherence interferometry using broadband multi-Gaussian light sources

et al. 2012

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Using a low coherence interferometry (LCI) model, a comparison of broadband single-Gaussian and multi-Gaussian light sources has been undertaken. For single-Gaussian sources, the axial resolution improves with the source bandwidth, confirming the coherence length relation that the resolution for single Gaussian sources improves with increasing spectral bandwidth. However, narrow bandwidth light sources result in interferograms with overlapping strata peaks and the loss of individual strata information. For multiple-Gaussian sources with the same bandwidth, spectral side lobes increase, reducing A-scan reliability to show accurate layer information without eliminating the side lobes. The simulations show the conditions needed for the resolution of strata information for broadband light sources using both single and multiple Gaussian models. The potential to use the model to study optical coherence tomography (OCT) light sources including super luminescent diodes (SLDs), as reviewed in this paper, as well as optical delay lines and sample structures could better characterize these LCI and OCT elements. Forecasting misinformation in the interferogram may allow preliminary corrections. With improvement to the LCI-OCT model, more applications are envisaged.

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Section: Tandem Sldsmentioning

confidence: 99%

Modeling of low coherence interferometry using broadband multi-Gaussian light sources

et al. 2012

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“…These spectral domain (SD) PS-OCT prototypes employed two spectrometer cameras, one for each orthogonal polarization channel. In order to reduce system complexity, cost, and alignment efforts, SD PS-OCT approaches based on single camera detection were developed [42,49,[84][85][86][87][88][89].…”

Section: Recent Advances In Ps-oct Technologymentioning

confidence: 99%

Polarization Sensitive Optical Coherence Tomography: A Review of Technology and Applications

Baumann

2017

Applied Sciences

135

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Polarization sensitive optical coherence tomography (PS-OCT) is an imaging technique based on light scattering. PS-OCT performs rapid two-and three-dimensional imaging of transparent and translucent samples with micrometer scale resolution. PS-OCT provides image contrast based on the polarization state of backscattered light and has been applied in many biomedical fields as well as in non-medical fields. Thereby, the polarimetric approach enabled imaging with enhanced contrast compared to standard OCT and the quantitative assessment of sample polarization properties. In this article, the basic methodological principles, the state of the art of PS-OCT technologies, and important applications of the technique are reviewed in a concise yet comprehensive way.

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“…Polarization-sensitive optical coherence tomography (PS-OCT) is an emerging noninvasive optical imaging technique that can provide cross-sectional images with high resolution approaching those of conventional histology and polarization information regarding collagenous tissues [12,13,14]. This later feature is useful because the birefringence of collagen fibers alters the polarization of the incident light which can be detected and quantified by PS-OCT [12,15,16].…”

Section: Introductionmentioning

confidence: 99%

The Use of Collagen Content as Determined by Spectral Domain Polarization-Sensitive Optical Coherence Tomography to Assess Colon Anastomosis Healing in a Rat Model

Son

Jeong²,

Jung

et al. 2014

Eur Surg Res

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Background/Purpose: Many studies have been undertaken to prevent anastomosis leakage of the colon, and several methods have been used to assess anastomosis healing, such as measurement of bursting pressure or hydroxyproline (a marker of collagen) content at the anastomosis site. However, these methods are inappropriate for comparing anastomosis healing at two time points in the same animals. In the present study, we measured the collagen level by spectral domain polarization-sensitive optical coherence tomography (SD-PS-OCT) to assess anastomosis healing. Methods: Sprague-Dawley rats were divided into groups C (saline-administered controls; study group) and M [a 5-fluorouracil (5-FU)-administered experimental group]. Immediately after end-to-end anastomosis of the colon, SD-PS-OCT images of anastomoses were taken (baseline). Animals were administered saline or 5-FU for 7 days. On the 7th postoperative day, SD-PS-OCT images were acquired, a histopathologic exam was performed, and hydroxyproline levels as well as mRNA expressions of collagen-1 and collagen-3 were measured at the anastomosis site. Results: Fibroblast proliferation and inflammatory cell infiltration were greater in group C than in group M. The mRNA expressions of collagen-1 and collagen-3 were substantially higher in group C. Hydroxyproline levels were higher in group M than in group C. Though collagen levels measured by SD-PS-OCT at 7 days were elevated compared with baseline in group C, no such changes were observed for group M. Conclusion: Collagen levels at the colon anastomosis site, measured with SD-PS-OCT, were not increased at 7 days postoperatively versus baseline when 5-FU was injected, but were increased in saline-treated controls. The measurement of collagen content by SD-PS-OCT was found to provide a good means of assessing anastomosis healing, because it allows in situ assessment of collagen contents at baseline and during the postoperative period.

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High-speed spectral domain polarization- sensitive optical coherence tomography using a single camera and an optical switch at 1.3 µm

Cited by 48 publications

References 15 publications

Modeling of low coherence interferometry using broadband multi-Gaussian light sources

Modeling of low coherence interferometry using broadband multi-Gaussian light sources

Polarization Sensitive Optical Coherence Tomography: A Review of Technology and Applications

The Use of Collagen Content as Determined by Spectral Domain Polarization-Sensitive Optical Coherence Tomography to Assess Colon Anastomosis Healing in a Rat Model

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