High-speed Freehand Tissue Elasticity Imaging for Breast Diagnosis

Tissue elasticity properties as biomarkers for prostate cancer

“…Since changes in tissue stiffness may be indicative of an abnormal pathological process, imaging parameters related to tissue elasticity may provide an effective biomarker for differentiating normal from cancerous tissues. In fact, several preliminary studies involving elasticity imaging of pathological tissues have supported this hypothesis, such as those dedicated to the detection of prostate [14][15][16][17][18][19][20] and breast [21][22][23][24][25][26][27] cancers using ultrasound-based approaches.…”

3D Myocardial Contraction Imaging Based on Dynamic Grid Interpolation: Theory and Simulation Analysis

“…Therefore, an accurate phase-shift cannot be obtained through a conventional autocorrelation method. To address this problem, we incorporate CAM (13) or ECAM (19) (20) into the WPGM as a phase-shift detector. Compared with the CAM, ECAM can detect beam direction's motion and lateral motion simultaneously.…”

“…Radio frequency (RF) signals for each scan line are received at all elements in the probe. The phase-shifts at every measuring point between two consecutive frames are calculated by the CAM (13) or the ECAM (19) (20) , and then the displacement vectors are calculated by WPGM (14) (15) from obtained phase-shifts. At the same time, the B-mode image, which is generated by the RF signals obtained from the aperture in the center transducer, is acquired.…”

“…In order to solve the above problems, a myocardial strain imaging system based on the combined autocorrelation method (CAM) (13) and the 3-D weighted phase gradient method (WPGM) (14) (15) , which can detect all directions' true displacement vectors, has been proposed previously (16)- (18) . In this research, in order to obtain a more accurate phase-shift, a new method which incorporates an extended combined autocorrelation method (ECAM) (19) (20) into the WPGM is proposed. The ECAM was originally proposed for detecting phase-shift and lateral motion simultaneously in tissue elasticity measuring.…”

Ultrasound elastography using multiple images

“…In this work, we perform displacement estimation for quasi-static ultrasound elastography , which involves deforming the tissue slowly with an external mechanical force and imaging the tissue during the deformation. More specifically, we focus on real-time freehand palpation elastography (Hall et al, 2003;Hiltawsky et al, 2001;Doyley et al, 2001;Yamakawa et al, 2003;Zahiri and Salcudean, 2006;Deprez et al, 2009;Goenezen et al, 2012) where the external force is applied by simply pressing the ultrasound probe against the tissue. Ease of use, real-time performance and providing invaluable elasticity images for diagnosis and guidEmail addresses: rivaz@jhu.edu (Hassan Rivaz), eboctor1@jhmi.edu (Emad M. Boctor), michael.choti@utsouthwestern.edu (Michael A. Choti), hager@cs.jhu.edu (Gregory D. Hager) URL: http://cs.jhu.edu/~rivaz/ (Hassan Rivaz) ance/monitoring of surgical operations are invaluable features of freehand palpation elastography.…”