High-speed chemical imaging inside a microfluidic channel

Miyamoto, Ko Ichiro; Itabashi, Akinori; Wagner, Torsten; Schöning, Michael J.; Yoshinobu, Tatsuo

doi:10.1016/j.snb.2013.12.090

Cited by 46 publications

(55 citation statements)

References 15 publications

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“…Sensor substrates were intrinsically the same as those used in our previous reports [9,10]. The surface of an n-type silicon wafer (1-10 ohm·cm, t = 200 μm) was insulated by a thermal oxide (SiO2) layer, then a layer of 50 nm silicon nitride (Si3N4) was deposited by LP-CVD as a sensing layer.…”

Section: Methodsmentioning

confidence: 99%

Restraining the Diffusion of Photocarriers to Improve the Spatial Resolution of the Chemical Imaging Sensor

Miyamoto

Suto

Werner

et al. 2017

Proceedings of Eurosensors 2017, Paris, France, 3–6 September 2017

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Abstract:The chemical imaging sensor is capable of visualizing the ion distribution. The spatial resolution of the chemical image depends on the horizontal diffusion of photocarriers generated by illumination. In this study; a novel optics is designed to realize a hybrid illumination of a ring of constant light and a spot of modulated light. Improved spatial resolution of the order of few tens of microns was successfully demonstrated.

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Section: Methodsmentioning

confidence: 99%

Restraining the Diffusion of Photocarriers to Improve the Spatial Resolution of the Chemical Imaging Sensor

Miyamoto

Suto

Werner

et al. 2017

Proceedings of Eurosensors 2017, Paris, France, 3–6 September 2017

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“…One possible parameter to control inside those microfluidic systems is the pH value. Besides active measurements [77,78], different techniques, e.g., a.c. Faradaic reactions [79], field-enhanced water dissociation in microscale bipolar membranes [80,81], or electrolysis at electrodes inside the channel [82,83] have been developed for active manipulation of the pH value inside those microstructures. For water electrolysis, where not only gas, but also protons and hydroxide ions are generated, the anodic (Equation (3)) and cathodic (Equation (4)) reactions can be described as follows:…”

Section: Addressable Photoelectrochemistrymentioning

confidence: 99%

Light-addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions

Welden

Schöning

Wagner

et al. 2020

Sensors

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In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semiconductor. Illumination with a light source with the appropiate wavelength leads to the generation of electron-hole pairs which can be utilized for further photoelectrochemical reaction. Due to recent progress in light-projection technologies, highly dynamic and flexible illumination patterns can be generated, opening new possibilities for light-addressable electrodes. A short introduction on semiconductor-electrolyte interfaces with light stimulation is given together with electrode-design approaches. Towards applications, the stimulation of cells with different electrode materials and fabrication designs is explained, followed by analyte-manipulation strategies and spatially resolved photoelectrochemical deposition of different material types.

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“…(49) The multiplicity was raised to 64, and an optical fiber bundle was used to deliver light beams from 64 LEDs to corresponding pixels densely arranged on the sensor plate. (50,51) A movie recording at a resolution of 8 × 8 pixels and a frame rate of 200 fps was realized. The use of an optical fiber bundle has another advantage that the pixel layout can be flexibly changed.…”

Section: Correction Of Artifact Signalmentioning

confidence: 99%

Development and Bio-imaging Applications of a Chemical Imaging Sensor

2016

Sensors and Materials

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A chemical imaging sensor is a field-effect-based semiconductor sensor, capable of label-free imaging of ion distributions in a solution. The sensor has attracted much interest owing to its simple structure and diverse fields of application of bioimaging. In this article, the principle and development of the chemical imaging sensor are summarized, compared with those of other labelfree imaging sensors. Bio-imaging applications of the chemical imaging sensor to ion diffusion, enzymatic reaction, and metabolic activities of microorganisms are also reviewed.

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High-speed chemical imaging inside a microfluidic channel

Cited by 46 publications

References 15 publications

Restraining the Diffusion of Photocarriers to Improve the Spatial Resolution of the Chemical Imaging Sensor

Restraining the Diffusion of Photocarriers to Improve the Spatial Resolution of the Chemical Imaging Sensor

Light-addressable Electrodes for Dynamic and Flexible Addressing of Biological Systems and Electrochemical Reactions

Development and Bio-imaging Applications of a Chemical Imaging Sensor

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