High serum laminin concentrations in patients with Candida sepsis

Presterl, Elisabeth; Lassnigg, Andrea; Mueller-Uri, P.; Wenisch, Christoph; El-Menyawi, I.; Graninger, Wolfgang

doi:10.1046/j.1365-2362.1999.00571.x

Cited by 6 publications

(2 citation statements)

References 29 publications

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“…C. albicans also has an effect on BM proteins. Indeed, Presterl et al (1999) reported that laminin concentrations are significantly higher in patients with Candida sepsis than in patients with bacterial sepsis. The present study and others suggest that infections by C. albicans are initiated by adhesion and are mediated by binding to several ECM host proteins.…”

Section: Discussionmentioning

confidence: 99%

Basement membrane protein and matrix metalloproteinase deregulation in engineered human oral mucosa following infection with Candida albicans

2004

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Section: Discussionmentioning

confidence: 99%

Basement membrane protein and matrix metalloproteinase deregulation in engineered human oral mucosa following infection with Candida albicans

2004

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“…Many species of the complex oral microbiota maintain a symbiotic relationship with the host (10)(11)(12). To maintain homeostasis within the oral cavity, the host has two distinct but interrelated immune response systems: the salivary immune system (13)(14)(15)(16) and the serum immune system (17,18). The changing balance of conditions in the mouth influences the stability and integrity of the oral mucosal tissues.…”

Section: The Oral Cavity Environmentmentioning

confidence: 99%

Interactions between Host and Oral Commensal Microorganisms are Key Events in Health and Disease Status

Rouabhia

2002

Canadian Journal of Infectious Diseases and Medical Microbiolog

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The oral cavity has sometimes been described as a mirror that reflects a person's health. Systemic disease such as diabetes or vitamin deficiency may be seen as alterations in the oral mucosa. A variety of external factors cause changes in the oral mucosa, thus altering mucosal structure and function, and promoting oral pathologies (most frequently bacterial, fungal and viral infections). Little is known, however, about immune surveillance mechanisms that involve the oral mucosa.There is no direct contact between specific immune cells in the basal epithelium and microorganisms in the upper layers of the oral mucosa. The author's hypothesis is that the protective immunity is conveyed through epithelial cells. The present brief review assesses the oral mucosa's role as the main defense in the interactions between the host and the oral microbial community. A unique model was used to investigate these interactions as the cause of oral disease and to develop new treatments that exploit our knowledge of the host-microorganism relationship.

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Circulating sICAM-1 and sE-Selectin as biomarker of infection and prognosis in patients with systemic inflammatory response syndrome

Pablo¹,

Monserrat²,

Reyes³

et al. 2013

European Journal of Internal Medicine

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High serum laminin concentrations in patients with Candida sepsis

Abstract: Laminin serum concentrations might be useful to differentiate nonbacterial, bacterial and fungal etiology.

Cited by 6 publications

References 29 publications

Basement membrane protein and matrix metalloproteinase deregulation in engineered human oral mucosa following infection with Candida albicans

Basement membrane protein and matrix metalloproteinase deregulation in engineered human oral mucosa following infection with Candida albicans

Interactions between Host and Oral Commensal Microorganisms are Key Events in Health and Disease Status

Circulating sICAM-1 and sE-Selectin as biomarker of infection and prognosis in patients with systemic inflammatory response syndrome

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