High sensitive photonic crystal multiplexed biosensor array using H0 sandwiched cavities

Abstract

Abstract. We theoretically investigate a high sensitive photonic crystal integrated biosensor array structure which is potentially used for label-free multiplexed sensing. The proposed device consists of an array of three sandwiched H0 cavities patterned above silicon on insulator (SOI) substrate; each cavity has been designed for different cavity spacing and different resonant wavelength. Results obtained by performing finite-difference time-domain (FDTD) simulations, indicate that the response of each detection unit shifts independently in terms of refractive index variations. The optimized design makes possible the combination of sensing as a function of location, as well as a function of time in the same platform. A refractive index sensitivity of 520nm/RIU and a quality factor over 10 4 are both achieved with an accompanied crosstalk of less than -26 dB. In addition, the device presents an improved detection limit (DL) of 1.24.10 -6 RIU and a wide measurement range. These features make the designed device a promising element for performing label-free multiplexed detection in monolithic substrate for medical diagnostics and environmental monitoring.

A Highly Accurate Refractive Index Sensor with Two Operation Modes Based on Photonic Crystal Ring Resonator

“…However, the application of PCCs are not limited to only sensors and their diverse applications in the field of optical communication have been demonstrated for years. In recent decades, different types of PC‐based optical sensors with different sensing applications have been demonstrated for the aim of gas, liquid, temperature, stress, biomedical, and chemical detection and measurement . For instance, the first measurement of RI with sensitivity, Q factor, and size of 200 nm/RIU, 400, and 10 µm 2 , respectively has been presented in 2004 .…”