High-resolution endoscopic imaging of the GI tract using optical coherence tomography

Early caries detection using optical coherence tomography: a review of the literature

“…41,42 The first commercial OCT instruments, developed by Humphrey Instruments, were based on the work of the group in Boston. Further developments including endoscopic OCT paved the way for new fields such as cardiovascular OCT and gastrointestinal OCT. [43][44][45] The introduction of ultrahigh-resolution OCT and spectral domain OCT has dramatically increased the diagnostic potential of OCT. 46,47 In the meantime, approximately 17 OCT equipment manufacturers share a current market of about $200 million with a growth rate of 34% p.a. This trend is expected to continue for the next several years, with revenues topping $800 million by 2012.…”

Combining Optical Coherence Tomography with Fluorescence Imaging

“…The potential of LCI for three-dimensional imaging in biological tissue was first realized in 1991 (Huang et al, 1991). Since the original work, a large number of papers have been published regarding various aspects of OCT. OCT has been successfully translated to various clinical applications including ophthalmology (Schuman et al, 2004), cardiology (Jang et al, 2005), gastroenterology (Bouma et al, 2000;Li et al, 2000;Sivak et al, 2000;Chen et al, 2007a), dermatology (Welzel et al, 2004), dentistry (Otis et al, 2000), urology (D'Amico et al, 2000), among others (Huang et al, 1991;Fujimoto et al, 1995;Brezinski et al, 1996;Tearney et al, 1997;Fujimoto et al, 2000;Fujimoto, 2003). Figure 1A shows a schematic of the time-domain OCT (TD-OCT) system.…”

Comprehensive esophageal microscopy by using optical frequency–domain imaging (with video)

“…4,5 In this study, the optical components of the catheter were positioned at the center of a photodynamic therapy balloon catheter (Advanced Polymer, Inc, Salem, NH) that had a diameter of 1.8 cm. This is illustrated schematically in Figure 2B.…”