High rate of hypoglycemia in diabetic pregnant women on use of glyburide

There were insufficient data comparing oral anti-diabetic pharmacological therapies with placebo/standard care (lifestyle advice) to inform clinical practice. There was insufficient high-quality evidence to be able to draw any meaningful conclusions as to the benefits of one oral anti-diabetic pharmacological therapy over another due to limited reporting of data for the primary and secondary outcomes in this review. Short- and long-term clinical outcomes for this review were inadequately reported or not reported. Current choice of oral anti-diabetic pharmacological therapy appears to be based on clinical preference, availability and national clinical practice guidelines.The benefits and potential harms of one oral anti-diabetic pharmacological therapy compared with another, or compared with placebo/standard care remains unclear and requires further research. Future trials should attempt to report on the core outcomes suggested in this review, in particular long-term outcomes for the woman and the infant that have been poorly reported to date, women's experiences and cost benefit.

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Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes

Brown

Martis

Hughes

et al. 2017

Cochrane Database of Systematic Reviews

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Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women

Musa

Syed

Mohamed

et al. 2021

Pharmacological Research

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High rate of hypoglycemia in diabetic pregnant women on use of glyburide

Abstract: Figure 1 Patients' results medications.

Cited by 2 publications

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Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes

Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes

Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women

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