High prevalence of symptomatic acute HIV infection in an outpatient ward in southern Mozambique: identification and follow-up

Abstract

Of patients reporting with fever, 3.3% were shown to be potentially due to AHI. High prevalence of AHI in southern African populations may warrant investigation of tools and target populations for AHI screening as a novel way to address HIV prevention.

A Cytokine Pattern That Differentiates Preseroconversion From Postseroconversion Phases of Primary HIV Infection

“…HIV RNA was quantified by applying a multilevel pooling scheme of 10 samples/pool as described and validated in previous works. 19 A subgroup of HIV-negative time-matched controls was selected by computer randomization.…”

Enhanced T cell activation in Plasmodium falciparum malaria-infected human immunodeficiency virus-1 patients from Mozambique

“…Plasmodium falciparum-associated HIV-1 (Pf/HIV) infection has been described in many sub-Saharan Africa countries and data from these countries account for most of the available clinical data regarding this co-infection (Chalwe et al 2009, Davenport et al 2010, Kiyingi et al 2010, Mills et al 2010, Serna-Bolea et al 2010, Naniche et al 2011. A relevant issue in malaria-endemic regions is the identification of HIV/AIDS patients among suspected cases of acute malaria (Mills et al 2010, Serna-Bolea et al 2010. Furthermore, HIV-1 infection is a risk factor for receiving an incorrect diagnosis of malaria (Berg et al 2008).…”

“…107(8): 985-992, December 2012 As leading causes of morbidity and mortality, malaria and human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) are two of the most important diseases in Africa (Idemyor et al 2007). Plasmodium falciparum-associated HIV-1 (Pf/HIV) infection has been described in many sub-Saharan Africa countries and data from these countries account for most of the available clinical data regarding this co-infection (Chalwe et al 2009, Davenport et al 2010, Kiyingi et al 2010, Mills et al 2010, Serna-Bolea et al 2010, Naniche et al 2011. A relevant issue in malaria-endemic regions is the identification of HIV/AIDS patients among suspected cases of acute malaria (Mills et al 2010, Serna-Bolea et al 2010.…”

Mobile Device for Disease Diagnosis and Data Tracking in Resource-Limited Settings

“…Previous studies have shown that rapid tests often fail to correctly identify weakly positive samples (19 ) such as those from recent HIV infections, which can constitute 0.3% to 3% of HIV-infected patients in high-risk populations with patients seeking care for bacterial sexually transmitted infections at sexually transmitted disease clinics and patients reporting fever in areas of high HIV prevalence (35,36 ). Furthermore, rapid tests operated in resource-limited settings have exhibited lower accuracy due in part to the difficulty in interpreting weak signals (18,19 ).…”