High prevalence of persistently infected animals from bovine viral diarrhea in Colombian cattle

Abstract

BackgroundBovine Viral Diarrhea Virus (BVDV) is associated with gastrointestinal, respiratory and reproductive diseases of livestock across the world that causes continuous economic losses in the cattle industry. This virus can establish a persistent infection (PI) in calves after the fetal infection, making BVDV positive catle carriers and primary reservoirs which will constantly transmit the virus to healthy and new-born animals. For this reason, the detection of the PI animals in herds is the first line of prevention of the viral infection.ResultsIn this study, PI animals were detected in five different regions of Colombia through RT-PCR techniques and confirmed by sequencing. BVDV genotypes were determined using one fragment of the 5’UTR. It was found a 7% BVDV prevalence in animals and 22% in farms; and genotype 1 was identified as a single genotype for all of the samples. All samples were BVDV 1a.ConclusionThis is the first report in Colombia with higher prevalence rates compared with other places in the world, turned out to be of great importance for the ranchers, the vaccine producers and animal health control parties.

Determinación de la seroprevalencia y factores de riesgo de diarrea viral bovina en una población de la provincia de Pamplona

“…En Colombia, se ha reportado la presencia de animales PI en diferentes regiones del país, con una prevalencia que oscila entre el 1 y 10 % de los animales positivos, los cuales, son los responsables de mantener la enfermedad en una población determinada (Quintero et al 2019). Igualmente, se han realizado diferentes estudios de seroprevalencia, que comprueban la presencia del virus (Mogollón et al 1990;Jaime et al 1996;Vera et al 2003;González-Bautista et al 2021;Martínez-Rodríguez et al 2021;Rúa Giraldo et al 2023).…”

Persistent bovine viral diarrhea virus subgenotype 1d infection in dairy heifer calves born within 38 days interval

“…According to published data, in the Americas, Asia, and Europe, BVDV-1b is the predominant subgenotype (Yesilbag et al 2017). In South America, BVDV-1a is the most prevalent subgenotype in Colombia and Uruguay (Barbosa et al 2019, Maya et al 2016, whereas BVDV-1b predominates in Argentina and Chile (Pecora et al 2014, Pizarro-Lucero et al 2006. In Brazil, BVDV-1a is the most frequently detected BVDV subgenotype, followed by BVDV-2b and HoBi-like (Flores et al 2018).…”

“…In Italy, Nogarol et al (2017) con rmed the presence of ve PI animals carrying a BVDV-2a strain. Valdez et al (2018) described PI animals with BVDV-1 in Peru, and Barbosa et al (2019) detected BVDV-1a in Colombia. In a case-control study conducted by Kadohira and Tajima (2010) in Japan, 41 PI cows were detected in 23 different farms between 2006 and 2007, without subgenotype determination.…”

Simultaneous Detection of Bovine Rotavirus, Bovine Parvovirus, and Bovine Viral Diarrhea Virus Using a Gold Nanoparticle-Assisted PCR Assay With a Dual-Priming Oligonucleotide System

“…Bovine viral diarrhea virus (BVDV) is a globally welldistributed pathogen that infects cows leading to great economic losses (Yarnall and Thrusfield, 2017;Reichel et al, 2018). BVDV belongs to the Pestivirus genus under family Flaviviridae (Charoenlarp et al, 2018;Quintero Barbosa et al, 2019). In addition to causing respiratory, gastroenteric, and reproductive diseases, intrauterine infection with BVDV can also result in a persistent infection, thereby generating a state of immunotolerance (Lanyon et al, 2014;Khodakaram-Tafti and Farjanikish, 2017).…”