High-performance integrated field-effect transistor-based sensors

Adzhri, R.; Arshad, M. K. Md; Gopinath, Subash C. B.; Ruslinda, A. Rahim; Fathil, M. F. M.; Ayub, R. M.; Nor, Mohd Jailani Mohd; Voon, C. H.

doi:10.1016/j.aca.2016.02.042

Cited by 34 publications

(13 citation statements)

References 154 publications

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“…The results show that the bionic E-nose can accomplish quantitative analysis of volatile compounds [52,53]. However, bioelectronic noses have some disadvantages such as short lifetime, poor repeatability and difficult mass production process [42,43]. …”

Section: Electronic Nose (E-nose)mentioning

confidence: 99%

Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges

Zhou

Luo

GholamHosseini

et al. 2017

Sensors

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This paper provides a review of the most recent works in machine olfaction as applied to the identification of Chinese Herbal Medicines (CHMs). Due to the wide variety of CHMs, the complexity of growing sources and the diverse specifications of herb components, the quality control of CHMs is a challenging issue. Much research has demonstrated that an electronic nose (E-nose) as an advanced machine olfaction system, can overcome this challenge through identification of the complex odors of CHMs. E-nose technology, with better usability, high sensitivity, real-time detection and non-destructive features has shown better performance in comparison with other analytical techniques such as gas chromatography-mass spectrometry (GC-MS). Although there has been immense development of E-nose techniques in other applications, there are limited reports on the application of E-noses for the quality control of CHMs. The aim of current study is to review practical implementation and advantages of E-noses for robust and effective odor identification of CHMs. It covers the use of E-nose technology to study the effects of growing regions, identification methods, production procedures and storage time on CHMs. Moreover, the challenges and applications of E-nose for CHM identification are investigated. Based on the advancement in E-nose technology, odor may become a new quantitative index for quality control of CHMs and drug discovery. It was also found that more research could be done in the area of odor standardization and odor reproduction for remote sensing.

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Section: Electronic Nose (E-nose)mentioning

confidence: 99%

Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges

Zhou

Luo

GholamHosseini

et al. 2017

Sensors

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“…Therefore, receptors with height less than 5 nm are preferable to be immobilized on FET for sensing. Adzhri et al (2016) experimentally studied the significance of length of probes on performance of FET sensor. They demonstrated that aptamer with shorter length than Debye screening effect length yields better conductivity and has higher performance ( Figure 16) (Kang et al 2007).…”

Section: Graphene In Biosensorsmentioning

confidence: 99%

“…Graphene based biosensor fabricated on bioresorbable silk can be transferred on surface of tooth for bacteria detection (Mannoor et al 2014) FIGURE 15. Effect of charge screening at the electrical potential of the device (Adzhri et al 2016) process. Aptamers are selected by in-vitro process namely systematic evolution of ligands by exponential enrichment (SELEX).…”

Section: Graphene In Biosensorsmentioning

confidence: 99%

“…Aptamers offer high sensitivity as it reduces screening effect and its length is within Debye length. Debye screening length is known as range or distance between immobilized target molecules and the surface of sensing platform which is separated by the screen of counter ion electrons attracted towards the sensing surface, called 'electrical double layer' ( Figure 15) (Adzhri et al 2016) A typical Debye length at room temperature is 5 nm in 5-10 mM buffer solution (Ohno et al 2010). Receptor and ligand reaction should occur within Debye length in order to ensure mobile charges on conducting channel are not affected by charges located outside Debye length.…”

Section: Graphene In Biosensorsmentioning

confidence: 99%

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Graphene for Biomedical Applications: A Review

Hamzah

Selvarajan

Majlis

2017

JSM

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“…20 Besides the latter advantages, ZnO is a semiconductor with a wide bandgap (3.37 eV) at room temperature, high exciting binding energy (62 meV) and large piezoelectric constant. 21 Thus ZnO nanoparticles are unique sensor materials, combining semiconductor and oxide properties, necessary for actuation as field-effect transducers (FET), an important feature when related to an electrochemical biosensor in which the electronic characteristics is paramount. 22 In addition, ZnO nanoparticles present low toxicity and high biodegradability, thus contributing to the generation of less dangerous wastes.…”

Section: Introductionmentioning

confidence: 99%

Determination of Chlorophenol in Environmental Samples Using a Voltammetric Biosensor Based on Hybrid Nanocomposite

Arruda¹,

Souza²,

Nogueira³

et al. 2016

J. Braz. Chem. Soc.

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In this work, a simple electrochemical biosensor for 4-chlorophenol was developed based on laccase immobilized on a hybrid nanocomposite (ZnO nanoparticles/chitosan), and incorporated in a carbon paste electrode. There are few biosensors in the literature for this specific pollutant because it tends to form polymeric films on the electrode, causing surface passivation or even enzyme inactivation. The carbon paste allowed the surface to be easily renewed by polishing, which amends this limitation. To optimize the experimental conditions, we used cyclic voltammetry and hydroquinone as a representative of phenolic compounds due to the high toxicity of chlorophenol, thus avoiding the generation of hazardous residues. After optimization, a calibration curve was constructed for 4-chlorophenol using differential pulse voltammetry, and a linear response was obtained from 1 to 50 µM, with a lower detection limit of 0.7 µM. The obtained biosensor showed high accuracy when employed in the analysis of industrial wastewater.

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High-performance integrated field-effect transistor-based sensors

Cited by 34 publications

References 154 publications

Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges

Identification of Chinese Herbal Medicines with Electronic Nose Technology: Applications and Challenges

Graphene for Biomedical Applications: A Review

Determination of Chlorophenol in Environmental Samples Using a Voltammetric Biosensor Based on Hybrid Nanocomposite

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