High-performance gel permeation chromatography with a new type of silica packing material

Background

“…Unger et al [9,10] and Kirkland [11,12] have described porous silica particles, and Sato et al [13] have discussed porous alumina for SEC. The first small particles introduced commercially for SEC were µ-Styragel (a trade name for microparticle cross-linked polystyrene gel) by Waters Associates, Milford, Massachusetts.…”

Errors caused by flowrate variation in high performance size exclusion chromatography (GPC) [gel permeation chromatography]

“…Alternatively, selectivity can be achieved by the application of the substoichiometric principle (2), which uses quantities of reagent sufficient to extract only part of the metal to be separated. Beside the necessity to remove any metal with a higher conditional extraction constant beforehand, application of substoichiometry is greatly complicated in the case of DDC by the formation of mixed Cl-DDC complexes (3,4) with many metals.…”

Microcapsules for Cell Transplantation: Design, Preparation, and Application

“…Microspheres made of porous glass were introduced by Haller in 1965 (17), and later microspheres for protein separation made of porous silica were introduced by Unger et al (18), Regnier and Noel (19), and Hashimoto et al (20).…”