High Nutritional-Related Risk on Admission Predicts Less Improvement of Functional Independence Measure in Geriatric Stroke Patients: A Retrospective Cohort Study

Kokura, Yoji; Maeda, Keisuke; Wakabayashi, Hidetaka; Nishioka, Shinta; Higashi, Sotaro

doi:10.1016/j.jstrokecerebrovasdis.2016.01.048

Cited by 59 publications

(50 citation statements)

References 30 publications

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“…The malnutrition risk was judged to be severe if GNRI was <82, moderate if it was >82 and <91, mild if it was >92 and <98, and no risk if it was >99. GNRI is an evaluation scale developed for elderly people aged ≥65 years, and it can be used for a prognostic prediction of survival of elderly stroke rehabilitation patients [8].…”

Section: Bedriddenmentioning

confidence: 99%

“…We used the CONUT score obtained by scoring the values of albumin, total cholesterol, and lymphocyte counts and accumulating the three scores as a nutritional index. The CONUT score is an indicator reflecting protein metabolism, lipid metabolism, and immunity, and the malnutrition level was evaluated in four stages: normal (CONUT score is 0-1), mild (2-4), moderate (5)(6)(7)(8), and severe (9-12). Table 3 shows the background factors of the targeted cases.…”

Section: Bedriddenmentioning

confidence: 99%

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Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Abe¹

2017

Geriatrics

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It has been a long time since there were many elderly people in Japan. The medical care and costs for the elderly are enormous, and research to lower the mortality rate of the elderly is needed. We retrospectively investigated the prognostic factors for the survival of elderly patients who were hospitalized in the medical ward of our hospital. In total, 277 patients who were hospitalized between 1 January 2014 and 31 May 2017, were included in the retrospective study. Univariate and multivariate analyses of items (vital signs, laboratory data, and so on) were performed, and significant differences between the survival group and death group were subjected to receiver operating characteristic curve analysis. Serum urea nitrogen levels and serum albumin levels provided a relatively high area under the curve (AUC). However, there was no item for which AUC exceeded 0.70, and setting the cutoff value in this study was difficult. For treating the elderly, it is important to carefully evaluate each patient's prognostic factors, including the demented state, renal function, and nutritional state; personalized treatment of each patient is also important.

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Section: Bedriddenmentioning

confidence: 99%

Section: Bedriddenmentioning

confidence: 99%

Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Abe¹

2017

Geriatrics

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“…[5][6][7][8][9][10] Sarcopenia is defined as an age-related involuntary loss of skeletal muscle mass and strength, and it results in physical disability, a poor quality of life and increased risk of death. [13][14][15][16] Previous studies have shown positive correlations between the GNRI and functional independence measures, such as activities of daily living (ADL) and quality of life, [13][14][15][16] however, the target GNRI for independent walking ability in maintenance hemodialysis patients is not clear. [13][14][15][16] Previous studies have shown positive correlations between the GNRI and functional independence measures, such as activities of daily living (ADL) and quality of life, [13][14][15][16] however, the target GNRI for independent walking ability in maintenance hemodialysis patients is not clear.…”

Section: Introductionmentioning

confidence: 99%

Geriatric Nutritional Risk Index for independent walking function in maintenance hemodialysis patients: A single‐facility retrospective cohort study

Tanaka¹,

Nishiyama

Yamamura

et al. 2018

Geriatrics Gerontology Int

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Aim The target Geriatric Nutritional Risk Index (GNRI) for patients on chronic maintenance hemodialysis is unclear. We aimed to determine the relationship between the GNRI and independent walking ability in such patients. Methods In the present retrospective cohort study, 90 patients receiving chronic maintenance hemodialysis were included. Logistic regression analyses were carried out to evaluate the relationship between the GNRI and independent walking ability. Receiver operating characteristic curve analysis was carried out to determine the cut‐off GNRI for predicting independent walking ability. Results Multivariate logistic regression analysis showed significant differences in age (odds ratio [OR] 0.8, 95% confidence interval [CI] 0.6–0.9), creatinine generation rate percentage (OR 1.1, 95% CI 1.0–1.2), GNRI (OR 1.4, 95% CI 1.1–1.8; P < 0.01) and urea removal rate (OR 0.3, 95% CI 0.1–0.9; P < 0.05). The cut‐off GNRI for independent walking ability was 86.7 (area under the curve 0.80, sensitivity 92.1%, specificity 66.7%, positive hit ratio 86.6%, negative hit ratio 78.3%). The factors correlated with survival in the univariate analysis were the GNRI, equilibrated Kt/V, urea removal rate, clear space rate, salt intake amount (P < 0.01), number of days of hospitalization and %creatinine generation rate (P < 0.05). The Cox proportional hazard regression model showed an OR of 0.77 (95% CI 0.32–1.8) at a GNRI <86/GNRI ≥86. In the multivariate survival analysis, we observed no significant differences in any of the factors. Conclusions GNRI was correlated with walking ability, which indicated that GNRI might predict future walking ability; also, a GNRI of 87 might be the target for maintaining walking ability. Geriatr Gerontol Int 2018; 18: 1556–1561.

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“…The increased GNRI during hospitalization was an independent explanatory factor for the functional recovery of rehabilitation . Furthermore, in older people, malnutrition on admission was not believed to affect the functional recovery . The study findings suggested that nutritional status during hospitalization was associated with ADL.…”

Section: Discussionmentioning

confidence: 74%

Change in number of potentially inappropriate medications impacts on the nutritional status in a convalescent rehabilitation setting

Kose

Hirai

Seki

2018

Geriatrics Gerontology Int

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Aim The association between potentially inappropriate medications (PIM) use and nutritional status is unclear in Japan. The aim of the present study was to establish whether PIM use during hospitalization affects the nutritional status among geriatric patients in the convalescing stage. Methods This retrospective longitudinal cohort study included consecutive geriatric patients admitted and discharged from convalescent rehabilitation wards between 2010 and 2016. Participants were divided based on the presence or absence of increased PIM from admission to discharge. Demographic data, laboratory data and the Functional Independence Measure were analyzed between groups. We used the 2015 American Geriatrics Society Beers Criteria to screen for PIM, and the primary outcome was the Geriatric Nutritional Risk Index at discharge. A multiple linear regression analysis was used to examine whether Geriatric Nutritional Risk Index at discharge was independently associated with increased PIM. Results In total, 643 participants (220 men, 423 women; interquartile range 73–85 years) were included in the present study. Multiple linear regression analysis for increased PIM, adjusting for confounding factors, showed that PIM use was independently and negatively correlated with Geriatric Nutritional Risk Index at discharge. In particular, first‐generation antihistamine, antipsychotic, benzodiazepine, proton pump inhibitor and non‐steroidal anti‐ inflammatory drug use increased significantly from admission to discharge. Conclusions Increased PIM might be a predictor of nutritional status in geriatric patients. Geriatr Gerontol Int 2019; 19: 44–50.

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High Nutritional-Related Risk on Admission Predicts Less Improvement of Functional Independence Measure in Geriatric Stroke Patients: A Retrospective Cohort Study

Cited by 59 publications

References 30 publications

Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Geriatric Nutritional Risk Index for independent walking function in maintenance hemodialysis patients: A single‐facility retrospective cohort study

Change in number of potentially inappropriate medications impacts on the nutritional status in a convalescent rehabilitation setting

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