High-Intensity Focused Ultrasound (HIFU) For the Prostate Cancer: 5-year Experience

It has been well known that the treatment time of high-intensity focused ultrasound (HIFU) surgery can be reduced by expanding the focal area per sonication. Previously, a dual-concentric transducer using phase-inverted signals was proposed to axially extend the focal area, but it has suffered from the deep notch point between two focal lobes. In this paper, we propose the improved HIFU transducer with dual-concentric aperture driven by phase-inverted multifrequency signals based on an inversion layer technique. The proposed transducer can generate the expanded focal zone with a significantly reduced level of the notch point between two focal lobes in the axial direction. The performance of the proposed transducer was investigated using finite element analysis simulation. The electrical impedance, one-way impulse response, and acoustic field of the transducer were simulated. Subsequently, the lesion volume was investigated by heat transfer simulation. In the proposed method, the level of the notch point was increased above -6 dB due to various phase interactions between the fundamental and harmonic frequency combinations and the inverted and noninverted frequency combinations. The -6-dB depth of field related to the necrotic lesion size was increased by 141% compared with the conventional single element transducer. Thus, the proposed transducer can be a potential way to enlarge coagulated lesion size resulting in a reduced overall treatment time of HIFU surgery.

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Phase-Inverted Multifrequency HIFU Transducer for Lesion Expansion: A Simulation Study

Kwon

Sung

Park

et al. 2018

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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High-Intensity Focused Ultrasound (HIFU) For the Prostate Cancer: 5-year Experience

Cited by 1 publication

References 27 publications

Phase-Inverted Multifrequency HIFU Transducer for Lesion Expansion: A Simulation Study

Phase-Inverted Multifrequency HIFU Transducer for Lesion Expansion: A Simulation Study

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