High-Dose Senna Compared with Conventional PEG-ES Lavage as Bowel Preparation for Elective Colonoscopy: A Prospective, Randomized, Investigator-Blinded Trial

Radaelli, Franco; Meucci, G.; Imperiali, G.; Spinzi, Giancarlo; Strocchi, Enrico; Terruzzi, Vittorio; Minoli, Giorgio

doi:10.1111/j.1572-0241.2005.00335.x

Cited by 75 publications

(61 citation statements)

References 25 publications

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“…The sennosides are generally used in combination with PEG. The use of sennosides without PEG combination is controversial (3). Enema is an agent that evacuates the distal colon and was a basic component of colonoscopy preparation before the introduction of PEG (2).…”

Section: Introductionmentioning

confidence: 99%

A new approach in bowel preparation before colonoscopy in patients with constipation: A prospective, randomized, investigator-blinded trial

et al. 2017

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Objective: Enema administration in the morning of routine colonoscopy is known to be useless. However, the potential bowel cleansing effects of distal colon emptying with enema prior to purgatives are not known. The aim of this study is to investigate the effects of enema use before purgatives in preparation for colonoscopy. Material and Methods:Two hundred twenty-seven patients were randomly assigned into three groups; enema before purgative use, enema after purgative use, and no enema. Patients were compared in terms of age, sex, BMI, Rome III constipation criteria, history of abdominal surgery, tolerance to the preparation procedure, complications during preparation such as nausea, vomiting, headache and dizziness, cecal insertion time, total duration of colonoscopy, polyp determination rate and colonic cleansing based on the Boston Bowel Preparation Scale. Results:One hundred two (44.9%) patients were male and 125 (55.1%) female. The mean age and BMI was 55.4±11.8 years and 28.8±4.7, respectively. No difference was observed between the groups in terms of sex, age, or BMI. The number of fulfilled Rome criteria and of previous abdominal surgeries were significantly higher in females than in men. Right colon Boston Bowel Preparation Scale score was higher in the group using enemas before purgatives than the scores of other groups. This improvement was statistically significant in the female patient group with higher constipation rate. Conclusions:Use of enemas before purgatives in patients with constipation significantly improves adequacy of right colon cleansing.

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Section: Introductionmentioning

confidence: 99%

A new approach in bowel preparation before colonoscopy in patients with constipation: A prospective, randomized, investigator-blinded trial

et al. 2017

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“…For example, Valverde et al and Chilton et al showed that senna either alone or in combination was associated with more effective colonic cleanliness than other regimens [20,21]. Radaelli et al concluded that high-dose (288 mg) senna was an effective alternative to a standard 4-liter PEG solution, with overall cleansing reported as excellent or good in 90.6% of the senna group and in 79.7% of the PEG group (p = 0.003) [18]. Moreover, Yenidogan et al claimed that administration of senna on the colonoscopy day was effective as a bowel preparation protocol, since only 9.3% of the patients were asked to repeat the examination [4].…”

Section: Discussionmentioning

confidence: 99%

“…The cecal intubation, withdrawal and total colonoscopy time, endoscopic diagnosis, and additional therapeutic procedures (including polypectomy) were recorded. At the end of the colonoscopy, the difficulty of the procedure was rated by the endoscopist using the scale (1 = easy, 2 = fairly easy, 3 = difficult, and 4 = failure to complete the procedure) which was previously used by Radaelli et al [18]. The quality of the colon cleansing was evaluated using the validated Ottawa Bowel Preparation Quality Scale (Table 1) [19].…”

Section: Colonoscopy Procedures and Data Collectionmentioning

confidence: 99%

Adding stewed apricot juice to sena improves the right-side and overall colon cleansing quality for colonoscopy preparation

Yaşar

Abut

Kayadibi

et al. 2017

FFHD

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Citation: Yasar B., Abut E, Kayadibi H., Akdogan F., Gonen C. Adding stewed apricot juice to senna improves quality of colon cleansing in preparation for colonoscopy. Functional Foods in Health and Disease 2017; 7(1):54-67 ABSTRACT Background: To achieve optimal colonoscopic examination, the bowel must be sufficiently cleansed. However, none of the currently available colonoscopy preparation regimens is safe, efficient, and comfortable. The aim of this study was to determine whether adding stewed apricot juice to senna increased patient comfort and improved bowel cleansing during colonoscopy preparation.Methods: Outpatients of both genders who were over 18 years old and were referred for elective colonoscopy were randomly allocated to drink stewed apricot juice with senna or senna by itself. The quality of the colon cleansing was evaluated using the Ottawa scale. Patient tolerance and adverse events were evaluated through the completion of a questionnaire. Results:The study included a total of 128 patients in the randomization procedure. A significantly greater cleansing effect was observed using stewed apricot juice plus senna in the right and transverse colon (p = 0.038, p = 0.037 respectively). It was also determined that in the stewed apricot juice plus senna group, overall cleansing was superior (p < 0.001), total colonoscopy (17.6 min vs. 22.8 min, p = 0.048) and cecal intubation (7.4 min vs. 11.2 min, p = 0.042) times were shorter, and the colonoscopy procedure was easier (79.4% vs. 49.2%, p < 0.001). No differences were observed between the groups with respect to patient acceptance, compliance, and adverse

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“…PEG kullan›m› ile barsak temizli¤inde elde edilen baflar›, Radelli ve arkadafllar› taraf›ndan desteklenmemekte, yüksek doz sennosidin PEG'e alternatif olabilece¤i ileri sürülmektedir. 34 Alt G‹S endoskopisinde kolon temizli¤inin iyi olmas› ifllemin baflar›s›nda büyük rol oynasa da tek bafl›na yeterli de¤ildir. ‹fllemi yapan hekimin deneyim ve sabr›, hastan›n uyumu, altta yatan hastal›k baflar›da önemlidir.…”

Section: Tart›flmaunclassified

The Effect of Different Bowel Preparation Methods on the Success of Lower Gastrointestinal Endoscopy

Erözgen¹,

Baş²,

Ersoy³

et al. 2011

Kolon Rektum Hast Derg

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ÖZET Amaç: Endoskopik incelemeler; tarama, tan›, tedavi, takip amaçlarla yap›lmaktad›r. Alt gastrointestinal sistem (G‹S) endoskopisi günümüzde tan› ve tedavi amac›yla yayg›n kullan›lan bir yöntemdir. Üst G‹S endoskopiden fark›, iflleme yönelik haz›rl›k sürecinin zorlu¤u ve barsak temizli¤inin yetersizli¤i nedeniyle ifllemlerin tekrar edilmesidir. Bu çal›flmam›zda, endoskopi ünitemizde alt G‹S'e yönelik incelemelerde baflar›s›zl›k nedenlerini irdeleyerek, bu oran› azaltma konusunda yap›labilecekleri inceledik. Materyal ve Metod: Vak›f Gureba E¤itim ve Araflt›rma Hastanesi endoskopi ünitesinde Ocak 2003-2010 Ocak ABSTRACT Purpose: Endoscopic examinations are done for several purpose like to diagnose, treat and follow. Nowadays, lower GIS endoscopy is the common method which is used for diagnose and treatment. The differences of upper GIS endoscopy are that the preperation to procedure was more difficult and sometimes repeated procedures were needed because of insufficient bowel cleaning. In this article, we studied failure causes and what we can do about decreasing this failure rate in lower GIS examinations in our endoscopy unit. Material and Methods: 13595 lower gastrointestinal endoscopy studies performed between January 2003 and

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High-Dose Senna Compared with Conventional PEG-ES Lavage as Bowel Preparation for Elective Colonoscopy: A Prospective, Randomized, Investigator-Blinded Trial

Abstract: An oral high dose of senna is a valid alternative to standard PEG-ES for outpatient colonoscopy preparation.

Cited by 75 publications

References 25 publications

A new approach in bowel preparation before colonoscopy in patients with constipation: A prospective, randomized, investigator-blinded trial

A new approach in bowel preparation before colonoscopy in patients with constipation: A prospective, randomized, investigator-blinded trial

Adding stewed apricot juice to sena improves the right-side and overall colon cleansing quality for colonoscopy preparation

The Effect of Different Bowel Preparation Methods on the Success of Lower Gastrointestinal Endoscopy

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