In group B, H. pylori eradication rate was 91.25%, which is higher than the ideal 80% eradication rate. The results of the present study show that adding the prescribed doses of vitamins E and C to antimicrobial therapy is effective in eradicating H. pylori infection.

Determination of the liver histological lesions with noninvasive tests is an important part of the diagnostic work-up of patients with non-alcoholic fatty liver disease (NAFLD). We aimed to determine the predictive value of noninvasive biochemical markers, serum prolidase enzyme activity (SPEA), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and AST/ALT ratio for the liver histological lesions. Fifty-four liver biopsy-proven patients with NAFLD and 37 healthy controls were enrolled to the study. The diagnostic accuracies of biochemical markers were evaluated by receiver operating characteristic (ROC) curves and multiple linear regression analysis to predict the degree of fatty infiltration, lobular inflammation, NAFLD activity score, and stage of fibrosis. The SPEA of patients with steatohepatitis is significantly increased compared with the patients with simple steatosis and controls (1,338 [1,138-1,624] U/l; 974 [768-1,160] U/l; 972 [862-1,122] U/l, shown as median [25th-75th interquartile range], respectively, P < 0.0001). SPEA was positively correlated with the grade of liver fatty infiltration, lobular inflammation and NAFLD activity score, and stage of fibrosis, (r = 0.377, P < 0.005; r = 0.443, P < 0.001; r = 0.457, P < 0.001; r = 0.321, P < 0.018, respectively). SPEA was the best predictor for distinguishing steatohepatitis from simple steatosis according to the ROC analysis (area under the curve [AUC]: 0.85). Multivariate analysis revealed that the most useful single test for predicting lobular inflammation, NAFLD activity score, and fibrosis was SPEA, and for predicting the fatty infiltration, it was ALT (P < 0.00001, P < 0.001, P < 0.0001, P < 0.0001, respectively). This study demonstrated that SPEA can accurately predict the degree and stage of all histological lesions in NAFLD. It could be helpful for distinguishing steatohepatitis from simple steatosis and reducing the need for liver biopsy in the majority of patients with NAFLD.

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This study was carried out to determine the nourishment preference and life table of the larvae and adults of Leptinotarsa decemlineata on the potato varieties of Agria, Pasinler, Marfona, Granola and Caspar. While the longest development duration in L. decemlineata was observed on the Granola variety, the shortest one was detected on the Caspar variety. The highest egg mortality in the Colorado potato beetle occurred on the Marfona variety, while the lowest mortality occurred on the Pasinler variety. The total mortality of immature stages of L. decemlineata was the highest on the Marfona variety and the lowest was on the Caspar variety. The highest larval mortalities were observed in the first larval stages. The highest daily fecundities on potato varieties were on the Granola variety and the highest total fecundities were on the Pasinler variety. However, the lowest values for both characteristics were on the Agria variety. The descending order of intrinsic rates of increase was Pasinler, Caspar, Agria, Marfona and Granola potato varieties. The highest net reproductive rates were on the Caspar variety and the lowest rates were on the Granola variety. The generation time was the longest in the Caspar variety and the shortest in the Pasinler variety. The Colorado potato beetle showed the least performance on the Marfona potato variety when considering the mortality of eggs and immature stages, total fecundity and net reproductive rate.