Hidradenitis Suppurativa Axillaris

Schenck, Samuel George

doi:10.1148/54.1.74

Cited by 10 publications

(4 citation statements)

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“…No radiationrelated adverse effects were observed [8]. In general, it was found that the earlier RT was given in the course of HS, the better the outcome [4,8,10]. These findings correspond well with those of our cohort.…”

Section: Discussionsupporting

confidence: 89%

“…Low-dose RT for HS, however, is associated with only mild short-term side effects. Occasionally, there may be temporary epilation [9][10][11]. This has been referred to as hair follicle destruction [18], but this seems a misinterpretation, because the hairs return within 2-3 months [18] [18].…”

Section: Discussionmentioning

confidence: 99%

“…The reported results, publication bias taken into consideration, have been encouraging. In several HS case series the therapeutic results ranged from marked improvement to complete resolution of symptoms [4,[7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

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Long-Term Follow-Up after Radiotherapy of Hidradenitis Suppurativa

Boer¹

2021

Dermatology

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Background: Patients with hidradenitis suppurativa (HS) are still often disappointed with the current treatments offered and there is a clear demand for more effective options. Since the late 1990s there has been a revival in the use of radiotherapy (RT) for different benign diseases, including HS. During the past 20 years one case series and some scattered case reports have described promising results of RT. Objectives: To evaluate the long-term efficacy of RT in early-stage HS. Methods: A postal survey-based long-term follow-up with simple factual questions of partly retrospective and partly contemporary characteristics was performed. Sixty-four patients (96 axillae), diagnosed with mild to moderate HS were irradiated with a orthovoltage unit with 100 kV, 3 mm Al or 200 kV, 0.5 Cu filtering, respectively. Four to six biweekly fractional doses ranging from 0.75 to 1 Gy up to a total dose of 6 Gy in one series, and in chronic cases followed by four daily fractions of 2 Gy up to a total dose of 14 Gy, were given. Late treatment toxicity and the rate of remission of the disease were evaluated. Results: The overall response rate of the survey was 64.1% with 40.6% (26/64) valid, complete questionnaires. In total, 40 axillae were irradiated in these 26 patients. After a median follow-up of 40 years (range 32–52) complete remission of the lesions occurred in 34 of the 40 sites (85%). None of the 26 patients with 40 irradiated sites reported adverse effects at the time of the survey. Conclusions: RT appears to be an effective treatment for early and mild HS in the majority of patients. In this case series, no side effects were reported after a median follow-up period of 40 years.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

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Long-Term Follow-Up after Radiotherapy of Hidradenitis Suppurativa

Boer¹

2021

Dermatology

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“…Patients with a single abscess responded in an average of 3 treatments and resolution of an affected axilla took an average of 7.8 treatments. All patients responded well to treatments with no recurrences and most pain was gone by 2–3 treatments [9].…”

Section: Resultsmentioning

confidence: 99%

Radiotherapy for Hidradenitis Suppurativa: A Systematic Review

et al. 2021

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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory dermatosis characterized by painful nodules, abscesses, sinus tracts, and scarring mainly in the intertriginous areas. Patients with HS often experience inadequate responses to traditional treatment consisting of lifestyle modification, topical and systemic antibiotics, hormonal modulators, biologics, and procedural modalities. Low-dose radiotherapy has been used in benign cutaneous conditions, including HS; however, there is a paucity of literature summarizing its evidence. Herein, we systematically review the current literature on the efficacy of radiotherapy for patients with HS. Summary: This systematic review of the published literature reports the patient demographics, treatment regimens, efficacy, and adverse effects of radiotherapy in the treatment of HS. The historic timeline of these publications highlights the changes in management recommendations, introduction of more standardized outcome measures, and enhancements in treatment options. Radiotherapy appears to be an option for patients with treatment-resistant HS or who are poor surgical candidates. However, there remains a paucity of consensus on proper candidate selection, dosing, efficacy, and safety of the short- and long-term effects of radiotherapy.

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Temporary X-Ray Epilation Therapy of Chronic Axillary Hidradenitis Suppurativa

Zeligman¹

1965

Arch Dermatol

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Hidradenitis Suppurativa Axillaris

Cited by 10 publications

References 0 publications

Long-Term Follow-Up after Radiotherapy of Hidradenitis Suppurativa

Long-Term Follow-Up after Radiotherapy of Hidradenitis Suppurativa

Radiotherapy for Hidradenitis Suppurativa: A Systematic Review

Temporary X-Ray Epilation Therapy of Chronic Axillary Hidradenitis Suppurativa

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