Temporary X-Ray Epilation Therapy of Chronic Axillary Hidradenitis Suppurativa

Hidradenitis suppurativa is a recurrent disease involving apocrine-bearing skin with a predilection for intertriginous areas, including genital skin. It has a highly variable clinical course. Mild cases may present as recurrent isolated nodules, while severe instances of the disease with chronic inflammation may lead to scarring, functional impairment, and rarely, squamous cell carcinoma. While genetic factors, patient characteristics, hormones and infection play a role in disease expression, a comprehensive understanding of the pathogenesis remains to be elicited. Additionally, effective treatment is largely unknown. While the mainstay of therapy had been surgery, and topical or systemic antimicrobial agents, other therapeutic modalities such as retinoids, hormonal therapy and immunosuppresive medications may also hold some promise.

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“…Several authors have reported the successful treatment of HS with radiotherapy. Long‐term side‐effects must be considered (69,70).…”

Section: Managementmentioning

confidence: 99%

Hidradenitis suppurativa: a review

2004

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“…Anecdotal reports of improvements obtained with other various treatment options have also been published over the years: radiation therapy, 35,36 Botulinum toxin, 37 anti TNF‐α antagonists 19 and PDT, 38,39 have been used with variable success.…”

Section: Introductionmentioning

confidence: 99%

Metformin for the treatment of hidradenitis suppurativa: a little help along the way

Verdolini

Clayton

Smith

et al. 2012

Acad Dermatol Venereol

138

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“…There was no mention of supplementary therapy in congruence with radiotherapy. No active lesions in treated sites were reported at follow-up periods ranging from months to years after treatment [11].…”

Section: Resultsmentioning

confidence: 99%

Radiotherapy for Hidradenitis Suppurativa: A Systematic Review

et al. 2021

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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory dermatosis characterized by painful nodules, abscesses, sinus tracts, and scarring mainly in the intertriginous areas. Patients with HS often experience inadequate responses to traditional treatment consisting of lifestyle modification, topical and systemic antibiotics, hormonal modulators, biologics, and procedural modalities. Low-dose radiotherapy has been used in benign cutaneous conditions, including HS; however, there is a paucity of literature summarizing its evidence. Herein, we systematically review the current literature on the efficacy of radiotherapy for patients with HS. Summary: This systematic review of the published literature reports the patient demographics, treatment regimens, efficacy, and adverse effects of radiotherapy in the treatment of HS. The historic timeline of these publications highlights the changes in management recommendations, introduction of more standardized outcome measures, and enhancements in treatment options. Radiotherapy appears to be an option for patients with treatment-resistant HS or who are poor surgical candidates. However, there remains a paucity of consensus on proper candidate selection, dosing, efficacy, and safety of the short- and long-term effects of radiotherapy.

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Temporary X-Ray Epilation Therapy of Chronic Axillary Hidradenitis Suppurativa

Cited by 23 publications

References 10 publications

Hidradenitis suppurativa: a review

Hidradenitis suppurativa: a review

Metformin for the treatment of hidradenitis suppurativa: a little help along the way

Radiotherapy for Hidradenitis Suppurativa: A Systematic Review

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