Hidden prevalence of chronic kidney disease in hypertensive patients: the strategic role of primary health care

Silva, L.S. da; Cotta, Rosângela Minardi Mitre; Moreira, Tiago Ricardo; Silva, R.G. da; Rosa, Carnen; Machado, Juliana Costa; Bastos, Mariana Araújo Pena

doi:10.1016/j.puhe.2016.02.029

Cited by 17 publications

(20 citation statements)

References 26 publications

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“…A previous study [16] screened 293 individuals for CKD through the GFR estimated by the formula Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and by analysis of proteinuria and albuminuria in urine of 24 hours. Of these, 113 individuals were diagnosed with CKD.…”

Section: Study Design and Subjectsmentioning

confidence: 99%

Non-linear progression of chronic kidney disease and associated factors in hypertensive patients: a 4-year cohort study

Silva¹,

Moreira²,

Silva³

et al. 2020

Preprint

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Background Recent studies suggest that the progression of chronic kidney disease (CKD) is not linear, but we do not have clear evidence on this issue, especially in hypertensive patients. We sought to evaluate the progression of CKD and associated factors over four years in a cohort of hypertensive patients. Methods We conducted a prospective cohort study during the years 2012 and 2016, with hypertensive patients diagnosed with CKD (n = 113). The progression of CKD was assessed through the evolution of the glomerular filtration rate (GFR) and the change in the stage of CKD between 2012 and 2016. Sociodemographic, economic, lifestyle, clinical, anthropometric, and biochemical variables were evaluated. The strength of the association between CKD progression and explanatory variables was assessed by odds ratio (OR) and their respective 95% confidence intervals using univariate and multivariate logistic regression. Results Regarding progression, 78.1% of the CKD patients did not progress over four years. When assessing the CKD trajectory (2012–2016) through the evolution of GFR, there was a mean reduction of 1.3 mL/min/1.73m² in four years. In the group that progressed, there was a reduction of 13 mL/min/1.73m², while in the group that did not progress, there was an increase of 2 mL/min/1.73m². In the multivariate analyses, age (p = 0.047), diabetes mellitus (DM) (p = 0.042), and urea (p = 0.050) were independently associated with CKD progression. Conclusions The findings of the present study showed a non-linear progression of CKD over the four years, contrary to what is traditionally expected. Age, DM and urea were independently associated with CKD progression.

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Section: Study Design and Subjectsmentioning

confidence: 99%

Non-linear progression of chronic kidney disease and associated factors in hypertensive patients: a 4-year cohort study

Silva¹,

Moreira²,

Silva³

et al. 2020

Preprint

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“…In developed countries, a prevalence of CKD is estimated between 10 and 16% in the adult population 4‐11 . In Brazil, its incidence and prevalence have increased considerably and with them the high costs of its treatment 12 .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of chronic kidney disease in Brazilians with arterial hypertension and/or diabetes mellitus

Comini

Oliveira

Borges

et al. 2020

J of Clinical Hypertension

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Chronic kidney disease (CKD) consists on the progressive and irreversible loss of kidney function, 1 being recognized as a global public health problem, with significant increase in the number of affected individuals. Patients with arterial hypertension (AH) and diabetes mellitus (DM) were identified as the main causes of the disease. 1-4 In developed countries, a prevalence of CKD is estimated between 10 and 16% in the adult population. 4-11 In Brazil, its incidence and prevalence have increased considerably and with them the high

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“…11 The evaluation of renal function is carried out by means of the estimation of Glomerular Filtration Rate (GFR), currently the method of estimation of the GFR is recommended with the CDK-EPI, [1][2][3][4][5][6][7][8][9][10][11][12] and by means of the determination of the ACR (Albuminuria/Creatinine Ratio), considering that the proteinuria is a marker of established renal damage and plays a direct pathogenic role in renal and cardiovascular progression, [1][2][3][4][5][6] the standard measurement has usually been the quantification of urine collected during 24 hours, to avoid errors in the collection, the determination of the ACR is recommended, which currently allows us to integrate the classification of the CKD together with the estimation of the GFR. [1][2][3][4][5][6] Salvador et al, 13 in Catalonia report a frequency of CKD of 18.8% in patients with SAH over 60 years of age, 13 Da Silva et al, 14 in Brazil, found a prevalence of CKD of 38.6% in patients with SAH, 14 Sánchez et al, 15 in Mexico, found a 6% frequency of CKD in patients with SAH. 15 Considering the wide variability in the frequency results of CKD, and the importance of early intervention in early and timely diagnosis, to reduce the progression of kidney disease, improve survival and quality of life, as well as decrease in costs of the treatment, the objective of this study was to estimate the frequency of kidney damage in adults with SAH in UMF 28 of IMSS in 2017.…”

Section: Introductionmentioning

confidence: 99%

Kidney damage in hypertensive adults in primary care

Fern

Rojas

Acosta

et al. 2018

IJFCM

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Hidden prevalence of chronic kidney disease in hypertensive patients: the strategic role of primary health care

Cited by 17 publications

References 26 publications

Non-linear progression of chronic kidney disease and associated factors in hypertensive patients: a 4-year cohort study

Non-linear progression of chronic kidney disease and associated factors in hypertensive patients: a 4-year cohort study

Prevalence of chronic kidney disease in Brazilians with arterial hypertension and/or diabetes mellitus

Kidney damage in hypertensive adults in primary care

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