Hexamethylenetetramine-based ionic liquid/MIL-101(Cr) metal–organic framework composite: a novel and versatile tool for the preparation of pyrido[2,3-d:5,6-d′]dipyrimidines

Abstract

In this study, HMTA-BAIL@MIL-101(Cr) was prepared as a novel catalyst for the synthesis of dipyrimidine derivtives by the reaction of barbituric acids, 6-aminouracil/6-amino-1,3-dimethyl uracil, and arylaldehydes under solvent-free conditions.

Developments of pyridodipyrimidine heterocycles and their biological activities

“…Mirhosseini-Eshkevari et al [ 78 ] synthesized compounds 43 under catalyzed conditions. The green protocol was accomplished under solvent-free, and nano-catalytic conditions.…”

Recent progress of nanocatalyst in the synthesis of heterocyclic compounds by barbituric acids

“…transformation, excellent yields, high potential recyclability, and reusable over six cycles with no appreciable loss in activity. 88 The preparation of (Cr)101-MIL@BAIL-HMTA was performed in three steps displayed in Scheme 77. In the first stage, the (Cr)101-MIL was synthesized under hydrothermal status with a mixture of chromium (III) nitrate nonahydrate, water, terephthalic acid (BDC), and hydrofluoric acid.…”

Ionic liquid immobilized on modified magnetic FSM-16: an efficient and magnetically recoverable nanocatalyst

“…Therefore, immobilization of ionic liquids on suitable solid supports such as porous supports or magnetic nanoparticles would be a short cut to achieve better catalytic efficiency and recycling performance than current ionic liquid catalysts. 29–33 To date, many ionic liquids supported on magnetic mesoporous materials have been prepared and used in many chemical reactions. Some of the recently developed systems are Fe 3 O 4 @silica-MCM-41@DABCO, 34 Fe 3 O 4 @MCM-41@IL/Pd, 35 MCM-41@ILLaCl 4 , 36 I@BFPMO-IL, 37 Fe 3 O 4 @MCM-41@ZrCl 2 , 38 Fe 3 O 4 @MCM-41-SO 3 H@[HMIm][HSO 4 ], 39 Fe 3 O 4 @MCM@IL-WO 4 = , 40 SBA-15/NHSO 3 H, 41 and Fe 3 O 4 @SiO 2 -HMTA-SO 3 H. 42 The heterogenization of IL catalysts can also be achieved by the construction of poly(ionic liquid)s, and several catalysts of this type have been reported.…”