Heterotopic pregnancy after in vitro fertilization–embryo transfer

Chin, Hung Yen; Chen, F.-P.; Wang, C.-J.; Shui, Liao; Liu, Y.-H.; Soong, Yung‐Kuei

doi:10.1016/j.ijgo.2004.05.011

Cited by 58 publications

(54 citation statements)

References 22 publications

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“…In addition, the interstitial region receives a very significant blood supply from the uterine and ovarian arteries branches. An HP after salpingectomy can be as much threatening as EP, because the tubal interstitium rupture may lead to a sudden and excessive blood loss, worsened also by hypervascularity due to the intrauterine pregnancy [34].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Ectopic Pregnancy of the Tubal Stump in ART Patients, Two Case Reports and a Review of the Literature

Mg¹,

Riganelli²,

Donfrancesco³

et al. 2017

Med Case Rep

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Section: Discussionmentioning

confidence: 99%

“…Tubal stump pregnancies can occur when the embryo or the oocyte migrate through the uterine cavity or when the oocyte passes through a tubal fistula [35]. A review of the literature conducted by Chin et al [34] reported 22 cases of cornual pregnancies after IVF-ET.…”

Section: Discussionmentioning

confidence: 99%

Ectopic Pregnancy of the Tubal Stump in ART Patients, Two Case Reports and a Review of the Literature

Mg¹,

Riganelli²,

Donfrancesco³

et al. 2017

Med Case Rep

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“…In particular, the biggest advantage of vaginal ultrasonographic guided drug administration is that anesthesia and surgery can be avoided. However, surgical treatment has to be used in cases where there is a risk of excessive bleeding if the ectopic mass ruptures, where abnormal location makes access for drug administration difficult, or where intrauterine gestation is close [4,7]. In addition, a cornual HP should be treated to maintain a normal intra-uterine pregnancy.…”

Section: Discussionmentioning

confidence: 99%

A live birth after laparoscopic cornual resection for cornual heterotopic pregnancy after IVF-ET

Lee

Eom

Koh

et al. 2012

Korean J Obstet Gynecol

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A 28-year-old Korean woman with a history of both salpingectomies due to two prior tubal pregnancies at other institutions conceived a heterotopic cornual pregnancy after in vitro fertilization-embryo transfer. The patient was referred to the emergency department with an abrupt onset of lower abdominal pain at the 7th gestational week. We performed an emergent laparoscopic right cornual resection. The subsequent antenatal course was unremarkable. There were no obstetric or surgery-related complications. The patient delivered a healthy baby of 3,340 g via Cesarean section due to failure to progress at term. Copyright © 2012. Korean Society of Obstetrics and GynecologyHeterotopic pregnancy (HP) is a rare complication of pregnancy in which intra-uterine and extra-uterine gestation occur simultaneously. The prevalence rate of HP is as rare as 1 in 30,000 natural gestations but increases to 1 in 100 pregnancies in women who have undergone an assisted reproductive technology (ART) procedure [1]. The incidence of cornual HP is estimated to be as high as 1 in 3,600 in vitro fertilization (IVF) pregnancies [2]. Cornual HP has a high risk of uterine rupture and is difficult to diagnose early. The main issue in the treatment of a cornual HP is to be as minimally invasive as possible to preserve the developing intrauterine pregnancy. We report the case of a cornual heterotopic pregnant woman who delivered a healthy baby after a successful laparoscopic cornual resection for a cornual HP that developed after the women underwent IVF-embryo transfer (ET). Case ReportA 28-year-old Korean woman, gravida 2, para 0, underwent IVF-ET because she had undergone two prior salpingectomies for tubal pregnancies at other centers. She was referred to the emergency department because she had experienced an abrupt onset of lower abdominal pain at the 7th gestational week. At initial presentation, her vital signs were stable and physical examination of the abdomen presented lower abdominal tenderness and rebound tenderness. A transvaginal ultrasonogram showed free fluid in the cul-de-sac and two gestational sacs (Fig. 1). One gestational sac was present in the right cornual area and the other was in the uterine cavity. Two separate yolk sacs and fetal parts were noted in each gestational sacs, but there were no fetal heart tones. We performed emergent laparoscopic surgery including right cornual resection. To minimize exposure of the fetus to anesthetic agents, general anesthesia was started after completion of the preparations of all laparoscopic surgical instruments and operation-related procedures. After the trocar was inserted, carbon dioxide pressure was CASE REPORT Korean J Obstet Gynecol 2012;55(8):610-613 http://dx

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“…Unfortunately, approximately 50% of heterotopic pregnancies present symptoms of tubal rupture. Surgery is usually required and MTX is contraindicated (Chin et al, 2004;Fernandez et al, 2004). In cases of heterotopic pregnancy with an association of intra-uterine pregnancy and non-tubal pregnancy with embryonic cardiac activity, an alternative treatment could be local injection of KCL under ultrasound guidance.…”

Section: Heterotopic Pregnancymentioning

confidence: 99%

Clinical Treatment of Unruptured Ectopic Pregnancy

Elito¹

2011

Ectopic Pregnancy - Modern Diagnosis and Management

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Heterotopic pregnancy after in vitro fertilization–embryo transfer

Abstract: These cases illustrate that good perinatal outcomes can be achieved by surgical intervention in heterotopic pregnancies, even in the event of a ruptured cornu.

Cited by 58 publications

References 22 publications

Ectopic Pregnancy of the Tubal Stump in ART Patients, Two Case Reports and a Review of the Literature

Ectopic Pregnancy of the Tubal Stump in ART Patients, Two Case Reports and a Review of the Literature

A live birth after laparoscopic cornual resection for cornual heterotopic pregnancy after IVF-ET

Clinical Treatment of Unruptured Ectopic Pregnancy

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