Hetero-Binuclear Complexes of Lanthanum (Iii) Using Bridging N,n?-Bis(2-Pyridylmethyl)oxamide and Terminal 1,10-Phenanthroline: Synthesis, Characterization and Biological Evaluation
Abstract:In the present study, hetero-binuclear La(III) complexes were newly synthesized using well known bridging ligand N,N′-bis(2-pyridylmethyl)oxamide (2PMO, 1) and “complexes as ligands” [Cu(2PMO)] (2) and [Ni(2PMO)] (3). The newly synthesized mononuclear (4) as well as hetero-binuclear complexes (5 and 6) were characterized by analytical and spectroscopic techniques. The newly synthesized complexes were tested for their binding ability towards CT-DNA and chemical nuclease property towards SC pUC 19 DNA. The compl… Show more
In this work, we presented the synthesis of igand [(2,2’-dibromo-1,2-diphenyethane-1,2-dione)-4-methy aniine](DPEMPA)by the reaction of (2,2’-dibromo-1,2-diphenyethane-1,2-dione) with 4-methy aniine under refux in ethano. The compexes of this igand have been prepared using meta acetates/chorides of Co(II), Ni(II), Cr(III), Cu(II) under refux in ethano-DMF. The products were found to be crystaine soid. The igand is characterized by anaytica, FT-IR, proton NMR spectra data whie compexes have been characterized by anaytica, FT-IR, TGA and magnetic susceptibiity measurements. The compounds were screened for antibacteria activity against some cinicay important bacteria, such asE. coi, S. typhy, S. aureus, P. aeruginosaand K. pneumonieby using nutrient agar medium and antifunga activity against C. abicansand A. niger species by using potato dextrose agar medium.
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