Synthesis, characterization, in vitro biological evaluation and molecular docking studies of newly synthesized mononuclear lanthanum(III) complexes of N,N'-bis(2-aminoethyl)oxamide and phenanthroline bases

Structural, electronic, intermolecular interaction, reactivity, vibrational spectroscopy, charge transfer, Hirshfeld surface analysis, pharmacological and hydropathy plot on 5-Bromo nicotinic acid – Antiviral study (Hepatitis A, B, and C)

“…The Chain A of the protein 2A4O, 6CWD and 2OC8 is selected along with its active site for the docking. The grid centre with dimensions (x, y and z) for the protein 2A4O is 0.455 points, 14.668 points and 31.700 points with a volume of 313 Å 3 , for 6CWD it is 145.664 points, −60.848 points and 317.057 points with the volume of 141 Å 3 and for 2OC8 it is 198.890 points, −4.387 points and 50.450 points with the volume of 152 Å 3 [ 97 , 98 ]. The visualisation of protein and ligand sites is done using the PyRx and BIOVIA Discovery Studio applications.…”

Recent Trends in the Development of Novel Metal-Based Antineoplastic Drugs

“…La(III) was complexed with N,N’-bis(2-aminoethyl)oxamide ( Figure 36 -1), 2,2′-bipyridine ( Figure 36 -2), 1,l0-phenanthroline ( Figure 36 -3) and dipyrido(3,2-a:2′,3′-c)phenazine ( Figure 36 -4) [ 130 ]. Four complexes were synthesized—[La(1) 2 (NO 3 ) 2 ](NO 3 ), [La(1)(2)](NO 3 ) 3 , [La(1)(3)](NO 3 ) 3 and [La(1) 2 (3)](NO 3 ) 3 .…”