Herpes zoster ophthalmicus with retrobulbar neuritis

Abstract

This is a rare case of HZO associated with retrobulbar neuritis. Prompt treatment with systemic antiviral and steroid improve the visual outcome.

Immunological criteria for predicting post-herpetic neuralgia

“…Главными индукторами синтеза ИЛ-1 являются пептидогликаны, липополисахариды и эндотоксины. К дополнительным индукторам относятся цитокины, иммунные комплексы, продукты аутолиза, ФНО-a, интерферон-a и интерферон-g, а также сам ИЛ-1b [6][7][8].…”

“…Интерфероны подразделяют на группы в зависимости от типа клеток, в которых они образуются: a, b и g [7][8][9].…”

Complete Recovery of Vision in Herpes Zoster Optic Neuropathy with Intravenous Acyclovir

“…1 In our review of literature, we retrieved 32 cases of HZON with a final visual outcome of 20/20 reported in 3 cases. [2][3][4] The presenting visual acuity was 20/200 in two cases and 20/120 in one case. [2][3][4] Since our patient started with CF vision, he represents the largest recovery to normal vision reported in literature.…”

“…[2][3][4] The presenting visual acuity was 20/200 in two cases and 20/120 in one case. [2][3][4] Since our patient started with CF vision, he represents the largest recovery to normal vision reported in literature. In the three cases that returned to 20/20, treatment included oral or intravenous corticosteroids in all cases.…”

“…In the three cases that returned to 20/20, treatment included oral or intravenous corticosteroids in all cases. [2][3][4] However, the use of corticosteroids in the treatment of HZON remains controversial as there are no randomized controlled trials or prospective studies to support its use. Opponents of corticosteroid use in HZON argue that there is a risk of VZV retinitis with evidence stemming from case reports of patients with optic neuropathies who were treated with corticosteroids when the diagnosis of herpetic disease was not yet established.…”