Herpes zoster might be an indicator for latent
 <scp>COVID</scp>
 19 infection

Elsaie, Mohamed L.; Youssef, Eman; Nada, Hesham

doi:10.1111/dth.13666

Cited by 96 publications

(119 citation statements)

References 17 publications

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“…Reactivation of HZ is not frequent in COVID-19 patients, but few cases raised the concerns of the possible association. A report of two cases has demonstrated HZ reactivation preceding the emergence of respiratory symptoms in COVID-19 patients [15]. Moreover, HZ may occur in entirely asymptomatic COVID-19 patients [16].…”

Section: Discussionmentioning

confidence: 99%

Herpes Zoster Co-Infection in an Immunocompetent Patient With COVID-19

Saati¹,

Al-Husayni²,

Malibari³

et al. 2020

Cureus

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a broad spectrum of manifestations. A variety of dermatological manifestations were described. We present a case of an immunocompetent middle-aged man who presented with novel coronavirus disease 2019 (COVID-19) and later developed herpes zoster (HZ). The case highlights the possibility of COVID-19-related HZ. The highest infection control measures must be abided when managing patients with cutaneous complaints until COVID-19 is ruled out.

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Section: Discussionmentioning

confidence: 99%

Herpes Zoster Co-Infection in an Immunocompetent Patient With COVID-19

Saati¹,

Al-Husayni²,

Malibari³

et al. 2020

Cureus

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show abstract

“…Earlier reports have described herpes zoster occurs before or after onset of COVID-19 symptoms with lymphopenia. 7,8 However, in this patient, herpes zoster occurred in the recovery period of COVID-19 and the results of clinical laboratory measurements were almost normal. This observation indicates the variety of COVID-19 and herpes zoster co-occurrence, and the complexity of the underling mechanisms.…”

Section: Discussionmentioning

confidence: 70%

“…6 Recently, there are case reports of herpes zoster in patients with both symptomatic and asymptomatic SARS-CoV-2 infection. 7,8 However, in these cases, no long-term follow up was performed and no postherpetic neuralgia was observed. Here, we report clinical features and treatments of herpes zoster and postherpetic neuralgia in an elderly patient with critical COVID-19.…”

Section: Introductionmentioning

confidence: 94%

Herpes Zoster and Postherpetic Neuralgia in an Elderly Patient with Critical COVID-19: A Case Report

Cao¹,

Zhang²,

Wang³

et al. 2020

JPR

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Critical patients with COVID-19 are thought to be at high risk of developing chronic pain. However, the exact nature and mechanisms of COVID-19-related chronic pain remain largely unknown. Here, we describe clinical features, treatments and outcome of herpes zoster as well as postherpetic neuralgia in a 70-year-old woman with critical COVID-19. The patient had a history of type 2 diabetes and myasthenia gravis. She developed herpes zoster in the right 10 to 12 lumbar dermatomes in the recovery period of COVID-19. Intravenous (250 mg 3 times a day) and then oral (400 mg 5 times a day) acyclovir was used for antiviral therapy. Pregabalin (75 mg orally twice a day) and ibuprofen was used for analgesia. Her skin lesions resolved 21 days after the onset of rash. However, she continued to have persistent pain in the same dermatomal distribution. After the dosage of pregabalin was increased to 150 mg orally twice a day, her pain was partially relieved. During the telephone follow-up 4 months after herpes zoster eruption, the patient still complained intermittent pain in the right 10 to 12 lumbar dermatomes. Our case draws attention to postherpetic neuralgia in COVID-19 patients and provides a targeted suggestion for this kind of patients.

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“…Patients with COVID-19 exhibit mild-moderate symptoms, with about 15% progressing to severe pneumonia and 5% eventually develop ARDS, septic shock and multiple organ failure and few patients are usually asymptomatic. 2 Patients present with fever, cough, breathlessness, diarrhoea, fatigue and some patients develop neurological symptoms like dizziness, headache, impaired consciousness, acute cerebro-vascular disease, seizures, ataxia and peripheral nerve involvement with loss of smell or taste and neuralgias. 3,4 Bell's palsy is defined as an isolated, sudden, peripheral facial paralysis of unknown etiology and patients usually show spontaneous recovery.…”

Section: Introductionmentioning

confidence: 99%

The surge of Bell’s palsy in COVID - pandemic era

Srinivas

Kauser

Sangoli

2020

Int J Otorhinolaryngol Head Neck Surg

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Background: COVID-19 is declared as a pandemic by WHO. Bell’s palsy is defined as isolated, sudden, peripheral facial paralysis of unknown etiology. Viral infections are capable of causing facial paralysis through infecting the motor neurons of brainstem, seventh nerve ganglia or through infections of supporting cells of the nerve, along with secondary inflammation and oedema, blocking the nerve function. Similarly, coronaviruses are known to have a neuroinvasive propensity.Methods: Our study was aimed to report the increased number of cases of Bell’s palsy in the current COVID pandemic era and to hypothesize the probable role of coronavirus in the pathogenesis of Bell’s palsy. A total of 30 patients presenting with unilateral facial palsy in this COVID era were included in the study. Results: This prospective analysis of Bell’s palsy cases showed 30 cases in the COVID pandemic era, where the total number of OPD patients were 3720. This shows a percentage of Bell’s palsy cases as 0.8 % when compared to 0.05% in the pre-covid time.Conclusions: This study shows that there might be an effect of COVID-19 virus on the immune status of the individuals along with stress induced reactivation of underlying viral infection.

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Herpes zoster might be an indicator for latent COVID 19 infection

Cited by 96 publications

References 17 publications

Herpes Zoster Co-Infection in an Immunocompetent Patient With COVID-19

Herpes Zoster Co-Infection in an Immunocompetent Patient With COVID-19

<p>Herpes Zoster and Postherpetic Neuralgia in an Elderly Patient with Critical COVID-19: A Case Report</p>

The surge of Bell’s palsy in COVID - pandemic era

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