Herpes Zoster in Children

Rogers, Roy S.

doi:10.1001/archderm.1972.01620110040010

Cited by 12 publications

(6 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…One report claimed that herpes zoster in otherwise healthy children was more severe than in adults (12). However, the indolent disease course in our series of patients is in line with what most other publications report (9,11–25,37–39). The absence of ZAP is the most striking clinical difference compared to adult herpes zoster.…”

Section: Discussionsupporting

confidence: 93%

“…The absence of ZAP is the most striking clinical difference compared to adult herpes zoster. We confirmed the frequent involvement of two dermatomes, without any further extradermatomal lesions, and the preferential thoracic location of the lesions (9,11–25,37–39). No systemic reactions such as fever, headache, or regional lymphadenopathy were recorded, in contrast to another report (39).…”

Section: Discussionsupporting

confidence: 78%

“…It usually affects elderly patients (1–3). More rarely, shingles may occur in immunocompromised (4–12) and immunocompetent children (9,11–25). The disease affects about 0.07% of children who are organ recipients or have malignancies at less than 9 years of age (1,26–29).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Revisiting Childhood Herpes Zoster

Nikkels

Nikkels‐Tassoudji²,

Pierard

2004

Pediatric Dermatology

View full text Add to dashboard Cite

Herpes zoster is rare in otherwise healthy children, but it is more common in association with immunosuppression. Maternal varicella infection during pregnancy and varicella occurring in the newborn represent risk factors for childhood herpes zoster. However, some controversies persist about risk factors, diagnosis, and the natural history of childhood disease. In a 2-year prospective study, 18 children with herpes zoster were clinically diagnosed in outpatient consultations in a hospital dermatology unit. Data about age, dermatome involvement, underlying disease, and history of previous varicella were recorded. Tzanck smears, biopsy specimens, and sera were obtained from 18, 4, and 10 children, respectively. The varicella zoster virus major envelope glycoprotein gE was detected in 16 of 18 smears and all four biopsies. Herpes simplex virus I was demonstrated in one of the smears. The established risk factors for childhood herpes zoster were only found in one child. Evidence for previous full-blown varicella and varicella with few lesions was recorded in 7 and 4 of the 17 immunocompetent children, respectively. No history of varicella was recalled in 6 of 17 cases, although a serologic clue of past varicella infection (IgM negative, IgG positive) was disclosed. Recurrent herpes zoster was diagnosed in one immunocompromised child. Zoster-associated pain was localized and the disease severity remained mild in all children. Established risk factors for childhood herpes zoster were only rarely found in our series of patients. In contrast, unrecognized varicella and varicella with few lesions were frequently recorded and may represent additional risk factors for shingles in childhood. Zosteriform herpes simplex virus infections should be differentiated from childhood herpes zoster, emphasizing the importance of precise viral identification.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 78%

See 1 more Smart Citation

Revisiting Childhood Herpes Zoster

Nikkels

Nikkels‐Tassoudji²,

Pierard

2004

Pediatric Dermatology

View full text Add to dashboard Cite

show abstract

“…Im Kindes-und Jugendalter wird davon ausgegangen, dass bestimmte Provokations-bzw. immunologische Risikofaktoren die Zostererkrankung begünstigen [2,10,11,23,24,25,28]. Hierzu zählen v. a. hämatologische Systemerkrankungen und vorausgegangene Knochenmarktransplantationen [2,6,11].…”

Section: Schlüsselwörterunclassified

“…Auch Knochenmarktransplantationen bzw. die im Anschluss daran notwendige immunsuppressive Therapie sind im Kindesalter als Risikofaktor für die Auslösung des Zoster beschrieben worden [10,11,23]. Zunehmende Bedeutung gewinnen seit einiger Zeit HIV-Infektionen nach intrauteriner Virusübertragung durch die Mutter [5,25].Auch die intrauterine Primärinfektion mit dem VZV und eine Erkrankung an Windpocken im 1.…”

Section: Verlauf Unter Intravenöserunclassified

Bilateraler asymmetrischer Zoster im Jugendalter

Bloss¹,

Ebisch²,

Kunz³

et al. 2001

Der Hautarzt

View full text Add to dashboard Cite

Zoster is a frequent disease of adulthood with a distinct age-dependent increase after 60. In contrast during childhood or adolescence zoster only rarely occurs. Certain risk factors such as hematologic malignancies are associated with early appearance. The typical clinical manifestation is unilateral, equally involving thoracic dermatomes. A 16-year-old patient presented with zoster in bilateral asymmetrical distribution, with trigeminal and thoracic dermatomes simultaneously affected. Despite the clinical findings and the unusual localization, there was no history, clinical nor laboratory signs of an immune suppression or any other underlying disease. Careful follow-up examinations are necessary in order to recognize systemic, especially hematologic, malignancies.

show abstract