Herpes Simplex Virus Disease of the Anterior Segment in Children

Serna‐Ojeda, Juan Carlos; Ramírez-Miranda, Arturo; Navas, Alejandro; Jiménez-Corona, Aída; Graue-Hernández, Enrique O

doi:10.1097/ico.0000000000000559

Cited by 17 publications

(29 citation statements)

References 12 publications

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“…Bilateral involvement can be particularly disabling and reported incidence in literature varies from 1.3% to 10.4% depending on the criteria used to diagnose it 3 4. It is more frequent in paediatric population and in individuals with immunocompromise from decreased T-cell function caused by atopy, asthma or other allergic disorders 5 6. Simultaneously occurring bilateral involvement is an even rarer phenomenon and although reported in a pregnant female using contact lenses, similar occurrence has yet not been reported in a lactating female 7…”

Section: Discussionmentioning

confidence: 99%

Bilateral herpes simplex keratitis: lactation a trigger for recurrence!

et al. 2019

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A young lactating woman presenting to us with simultaneous bilateral corneal lesions was clinically diagnosed to have herpes simplex keratitis, which was confirmed by herpes simplex virus (HSV) PCR. The patient was administered topical and systemic acyclovir therapy and therapeutic penetrating keratoplasty was done in right eye. She was advised to continue breast feeding under strict hygienic conditions. Diagnosis and management of HSV keratitis in a lactating patient can be particularly challenging for both clinician and patient and adoption of a multidisciplinary approach is necessary to ensure safety of mother and child. At 3 months follow-up, the baby was clinically healthy, there were no side effects of acyclovir therapy in the mother or the baby and the patient showed no evidence of recurrence in either eye.

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Section: Discussionmentioning

confidence: 99%

Bilateral herpes simplex keratitis: lactation a trigger for recurrence!

et al. 2019

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“…Although in our paper there is no specific mention to ophthalmic HSV involvement in children, the overall contemporary approach is similar to that in adults with the main difference lying in adjusting the dose and formulation (liquid suspension) of the oral antiviral …”

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confidence: 98%

Herpes simplex virus keratitis: an update of the pathogenesis and current treatment with oral and topical antiviral agents – response

Tsatsos

MacGregor

Athanasiadis

et al. 2016

Clinical Exper Ophthalmology

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“…Previous reports have addressed the clinical characteristics, complications, and recurrence rate of HSV keratitis in children; however, literature regarding the long-term outcomes of corneal transplantation in these patients is scarce. [5][6][7][8][9][10] The aim of this study is to analyze the characteristics of children that underwent PPK for HSV keratitis and to report their long-term outcomes.…”

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confidence: 99%