Herpes Gestationis

Smith, Janine A.

doi:10.1111/j.1471-0528.1953.tb06420.x

Cited by 8 publications

(1 citation statement)

References 16 publications

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“…Her baby had an ex tensive eruption with IgG and complement deposit on the dermo-epidermal junction compatible with the diagnosis of herpes gestationis. We found only 16 observations in the scientific literature concerning a pos sible transmission of the disease to the child [1,[4][5][6][8][9][10][11][12][13][14][15][16][17], The skin lesions may be present at birth [6,9], or may occur later, un til the 5th day of life [10], The pattern of these lesions is variable: features of bullous pemphigoid of the scalp [6], a few bullae [11] or vesicles on the chin [9], typical herpes gestationis [8,12], severe bullous dermatosis [13], transient rash preceding the onset of polycyclic papules forming vesicles 8 days later [4], lesions of erythema multiforme [10] on lower limbs, 3-cm-wide annular erythematous bands with blistering evolu tion [13], or discrete facial erythematous papules [1] with a few pustules.…”

Section: Commentsmentioning

confidence: 77%

Herpes gestationis in Mother and Erythemato-Pustulous Rash in the Newborn with Positive Direct Immunofluorescence

Guillet

Nougué²,

Oksman³

1988

Dermatology

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A 24-year-old secundigravida presented at 38 weeks of amenorrhea with typical cutaneous lesions of herpes gestationis. The newborn developed a skin rash 3 days after birth. The rash clinically resembled erythema toxicum neonatorum with dermal infiltrate of lymphocytes and eosinophilic polymorphonuclear cells forming a few intraepidermal pustules. The complement-binding antibody test for herpes gestationis factor was negative, but direct immunofluorescence study on this biopsy demonstrated a linear deposit of IgG and complement on the basement membrane zone. The possible transmission of the disease to the newborn is discussed.

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