Heritability of 39 orthodontic cephalometric parameters on MZ, DZ twins and MN-paired singletons

Manfredi, C; Martina, R; Grossi, Giovanni Battista; Giuliani, Michele

doi:10.1016/s0889-5406(97)70301-9

Cited by 87 publications

(85 citation statements)

References 11 publications

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“…1 Until recently, the vast majority of research has focused on the heritability of malocclusion and craniofacial morphology among siblings, with the twin model being the most popular method used. [1][2][3][4][5][6][7][8][9] Research comparing parents with their offspring has been limited because of the fact that tooth loss, restorative, prosthetic, and orthodontic treatment of older generations makes these investigations difficult.…”

Section: Introductionmentioning

confidence: 99%

Cephalometric craniofacial features in Saudi parents and their offspring

Alkhudhairi

Alkofide

2010

The Angle Orthodontist

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Objective: To estimate the correlation and heritability values of craniofacial variables between parents and their offspring. Materials and Methods: The sample comprised 24 Saudi families; each family consisted of father, mother, son, and daughter. Lateral cephalometric radiographs were taken for each family member. Twenty-eight angular, linear, and proportional cephalometric variables were measured. Interfamilial correlations and heritability (h 2 ) values were estimated among father-son, father-daughter, mother-son, and mother-daughter pairings. Results: The most similar angular measurements between parents and offspring were related to mandibular variables, which were as follows: MP-SNu, MP-FHu, SNBu, and SNPogu; facial height dimensions and mandibular body length were among the highest similar linear variables. Lower facial height percentage had greater resemblance to parents with regard to proportional measurements. Both the correlation coefficients and the heritable values of these characteristics were stronger in the father-offspring than the mother-offspring pairings. The daughters' cephalometric craniofacial characteristics were more affected by the parents than were those of the sons. Conclusions: The overall correlation and h 2 mean values for the three types of measurements showed stronger values in the father-offspring than the mother-offspring groups, with the fatherdaughter pairings more significant than the father-son groups.

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Section: Introductionmentioning

confidence: 99%

Cephalometric craniofacial features in Saudi parents and their offspring

Alkhudhairi

Alkofide

2010

The Angle Orthodontist

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“…Lobb (21) and Manfredi et al (22) reported that facial and dental cephalometric parameters have high heritability. Additionally, Hunter (11), Manfredi et al (22) and Lundström and McWilliam (23) suggested that the vertical parameters have a higher genetic control when compared with the horizontal ones.…”

Section: Discussionmentioning

confidence: 99%

Tek Yumurta İkizlerinin Farklı Tedavileri: Çenelik mi. Yüz Maskesi mi?

Altuğ¹,

Özdemir²,

Oz³

et al. 2006

Turkish Journal of Orthodontics

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“…(King et al, 1993) Numerous studies have examined how genetic variation contributes to either or both occlusal and skeletal variation among family members. (Arya et al, 1973;Boraas et al, 1988;Byard et al, 1985;Cassidy et al, 1998;Chung & Niswander, 1975;Corruccini et al, 1986;Devor, 1987;Fernex et al, 1967;Gass et al, 2003;Harris et al, 1973;Harris et al, 1975;Harris & Smith, 1980;Harris & Johnson, 1991;Hauspie et al, 1985;Horowitz et al, 1960;Hunter et al, 1970;Johannsdottir et al, 2005;King et al, 1993;Kraus et al, 1959;Litton et al, 1970;Lobb, 1987;Lundstrom & McWilliam, 1987;Manfredi et al, 1997;Nakata et al, 1973;Nikolova, 1996;Proffit, 1986;Saunders et al, 1980;Susanne & Sharma, 1978;Watnick, 1972) In most studies (particularly those that try to account for bias from the effect of shared environmental factors, unequal means, and unequal variances in monozygotic and dizygotic twin samples), (Harris & Potter, 1997) variations in cephalometric skeletal dimensions are associated in general with a moderate to high degree of genetic variation, whereas in general, variation of occlusal relationships has little or no association with genetic variation. (Harris, 2008) Although the heritability estimates are low, most of the studies that looked at occlusal traits found that genetic variation is positively correlated with phenotypic variation for arch width and arch length more than for overjet, overbite, and molar relationship.…”

Section: Heritability and Malocclusionmentioning

confidence: 99%