Hereditary Influences in Psoriasis

Lerner, Charles

doi:10.1038/jid.1940.30

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Diabetes1

Family History and Inheritance1

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1958

1974

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Cited by 15 publications

(2 citation statements)

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“…In a series of 100 children with psoriasis, Asboe-H ansen [1] found 38 who had a sore throat as a provoking mechanism in the course of their disease. He concluded that streptococcal infections may be responsible for psoriasis outbreaks in individuals who are genetically predisposed.…”

Section: Diabetesmentioning

confidence: 99%

The Natural History of Psoriasis in 5,600 Patients

Ml²

1974

Dermatology

542

321

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The natural history of psoriasis was studied through a questionnaire survey of 5,600 patients throughout the United States. The mean age of onset of psoriasis was 27.8 years. 36% of the respondents reported familial occurrence of the disease. At the time of study, the lower extremities were indicated as being the most often affected; trunk, elbow, and scalp were next, knee and face were cited less frequently. Fingernails were involved in half of the patients at some time during the period of their disease. In the majority of patients, hot weather and sunlight had a beneficial effect. One third of the females also indicated improvement during the course of pregnancy. Remissions were reported in 39% of the patients.

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Section: Diabetesmentioning

confidence: 99%

The Natural History of Psoriasis in 5,600 Patients

Ml²

1974

Dermatology

542

321

View full text Add to dashboard Cite

show abstract

“…His 3 siblings (II-6, 11-11, and 11-12) had, in all, 18 offspring who have grown to maturity. Of these, 7 The Table shows the segregation which has taken place in the families of the 5 affected parents. Of 41 children produced, the condition of 11 is unknown, 11 are affected, and the remainder are normal.…”

Section: Family History and Inheritancementioning

confidence: 99%