Hereditary Elliptocytosis Associated with Pernicious Anaemia

Abstract

A patient with hereditary elliptocytosis and pernicious anaemia is described. After the treatment with hydroxocobalamin the patient’s clinical condition and blood picture became entirely normal, except the persistence of elliptocytes of hereditary origin. Gene interaction was not encountered.

Acute lymphoblastic leukaemia in a child with hereditary elliptocytosis

“…Hereditary elliptocytosis is an inherited red blood cell membrane disorder characterized by typical peripheral blood smear findings of elliptocytes and has been described in association with other haematologic disorders, including HbS, β‐thalassaemia, HbC, pernicious anaemia and ALL 1,2 . However, the concurrence of HE with ALL is extremely rare with only one case reported in 1962, 2 and the genetic association between these two diseases remains unclear.…”