2011
DOI: 10.1002/14651858.cd002948.pub2
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Herbal therapy for treating rheumatoid arthritis

Abstract: Analysis 1.10. Comparison 1 Gamma-linolenic acid versus placebo, Outcome 10 Participants (n) reported reduced NSAID use..... Analysis 1.11. Comparison 1 Gamma-linolenic acid versus placebo, Outcome 11 Participants (n) reported adverse events......... Analysis 1.12. Comparison 1 Gamma-linolenic acid versus placebo, Outcome

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Cited by 94 publications
(97 citation statements)
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“…We analysed data from SRs of AEs of specific HMs and omitted SRs of polyherbal preparations and effectiveness reviews (see Supplemental Table S3). [63][64][65][66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81] It was frequently impossible to differentiate between herb-drug interactions and AEs, as these questions were addressed simultaneously. Herb-drug interactions, adulteration and contamination obviously can also cause AEs.…”
Section: Resultsmentioning
confidence: 99%
“…We analysed data from SRs of AEs of specific HMs and omitted SRs of polyherbal preparations and effectiveness reviews (see Supplemental Table S3). [63][64][65][66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81] It was frequently impossible to differentiate between herb-drug interactions and AEs, as these questions were addressed simultaneously. Herb-drug interactions, adulteration and contamination obviously can also cause AEs.…”
Section: Resultsmentioning
confidence: 99%
“…The anti-inflammatory and antiarthritic activities of many Chinese herbs have been validated in experimental models of arthritis and tested in clinical trials in RA patients [8][9][10][11]. However, the majority of clinical trials on herbal products suffer from deficiencies either in the quality of the test product or in the experimental design, or both [5,[10][11][12]. Variations in the composition or potency of the herbal formula might in part be owing to geographical or seasonal variations.…”
mentioning
confidence: 99%
“…Among the herbal TCM trials, those using Tripterygium wilfordii hook F (TwHF) (aka Thunder God Vine) are perhaps the most reliable [10,12,13]. These were done using a well-characterized herbal extract and tested in randomized controlled trials.…”
mentioning
confidence: 99%
“…4,10 Avocado/soybean unsaponifiables (ASU) constitute a medication produced from the fruits and seeds of these two plants in a 1:2 ratio (avocado/soy), and this medication is indicated for the treatment of rheumatoid arthritis and osteoarthritis. 11 This medication is considered to be a structural modifier of the joint tissues that were previously destroyed by the progression of arthritis/osteoarthritis. 12,13,14,15 The mechanism of action of this medication may make it applicable as a possible adjunctive agent for periodontal treatment.…”
Section: Introductionmentioning
confidence: 99%