Herbal Products That May Contribute to Hypertension

Jalili, Jamal; Askeroglu, Ufuk; Alleyne, Brendan; Guyuron, Bahman

doi:10.1097/prs.0b013e318272f1bb

Cited by 30 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A review based on five electronic literature databases summarizing the adverse cardiovascular and pressure effects of herbal medicines did not include H procumbens among the substances that cause hypertension . More recently, Jalili and colleagues reviewed 56 articles published from 1991 to 2011 focusing on the association between herbal products and hypertension; the authors were able to identify 29 papers providing reliable information about the hypertensive effects of herbal agents. In this updated review, the list of herbal products associated with hypertension (including as many as 16 substances such as arnica, bitter orange, blue cohosh, dong quai, ephedra, ginkgo, ginseng, guarana, licorice, pennyroyal oil, Scotch broom, senna, southern bayberry, St John's wort, and yohimbine) did not include H procumbens .…”

Section: Discussionmentioning

confidence: 99%

Systemic Hypertension Induced by Harpagophytum procumbens (devil's claw): A Case Report

Cuspidi

Sala

Tadić

et al. 2015

J of Clinical Hypertension

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Systemic Hypertension Induced by Harpagophytum procumbens (devil's claw): A Case Report

Cuspidi

Sala

Tadić

et al. 2015

J of Clinical Hypertension

View full text Add to dashboard Cite

“…In recent years, traditional Chinese medicine has shown its advantage against hypertension and hypertension-related complications [ 15 ]. Qian Yang Yu Yin Granule (QYYYG), a traditional Chinese herbal medicine, has been indicated for renal damage in hypertension for decades in China, but little remains known regarding its underlying molecular mechanism.…”

Section: Introductionmentioning

confidence: 99%

Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway

Ding

Wang

Jiang

et al. 2015

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundQian Yang Yu Yin Granule (QYYYG), a traditional Chinese herbal medicine, has been indicated for renal damage in hypertension for decades in China, but little remains known regarding its underlying molecular mechanism. Therefore, we performed the current study in order to investigate the underlying molecular mechanism of QYYYG in the treatment of hypertensive renal damage.MethodsWe hypothesize that QYYYG relieves hypertensive renal injury through an angiotensin II (Ang II)-nicotinamide adenine dinucleotide phosphate (NAPDH)-oxidase (NOX)-reactive oxygen species (ROS) pathway. In this study, we investigated the effects of QYYYG-containing serum (QYGS) in human mesangial cells (HMCs) against Ang II-induced cell proliferation, ROS production, and inflammation through the seropharmacological method.ResultsWe found that QYGS could inhibit cell proliferation in Ang II-treated HMCs. In addition, QYGS considerably suppressed production of ROS, decreased mRNA and protein expression of NAPDH-oxidase 4 (NOX4), p22phox, and activated Ras-related C3 botulinum toxin substrate 1 (GTP-Rac1); as well as counteracted the up-regulation of inflammatory markers including tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB) p65, and interleukin 6 (IL-6). These effects were further confirmed in HMCs transfected with specific small interfering RNA (siRNA) targeting NOX4.ConclusionsTaken together, these results suggest that a NOX4-dependent pathway plays an important role in regulating the inhibitory effect of QYGS. Our findings provide new insights into the molecular mechanisms of QYYYG and their role in the treatment of hypertensive nephropathy.

show abstract

“…Despite the reported benefits of NPs and MBPs, there must also be consideration for potential harmful effects of IM. In studies with an undefined level of evidence, reported theoretical risks of popular herbal remedies included perioperative hypertension (ginkgo and ginseng), 48 hemostasis complication (garlic and ginger), 49 and potential anesthesia risks (St John's wort, kava, and valerian). 50 Studies included in our systematic review questioned the safety of NP use and cautioned plastic surgeons on their application in perioperative patients, especially for garlic and gingko use because of a risk of bleeding complications.…”

Section: Discussionmentioning

confidence: 99%

Integrative Medicine in Plastic Surgery

Ruan¹,

Chen²,

Tran³

et al. 2019

Ann Plast Surg

View full text Add to dashboard Cite

Background: Surveys have reported that as high as 80% of plastic surgery patients utilize integrative medicine approaches including natural products (NPs) and mind-body practices (MBPs). Little is known regarding the evidence of benefit of these integrative therapies specifically in a plastic surgery patient population. Methods: We conducted a systematic review of studies in MEDLINE, PubMed, and EMBASE (inception through December 2016) evaluating integrative medicine among plastic surgery patients. Search terms included 76 separate NP and MBP interventions as listed in the 2013 American Board of Integrative Health Medicine Curriculum. Two independent reviewers extracted data from each study, including study type, population, intervention, outcomes, conclusions (beneficial, harmful, or neutral), year of publication, and journal type. Level of evidence was assessed according to the American Society of Plastic Surgeons Rating Levels of Evidence and Grading Recommendations. Results: Of 29 studies analyzed, 13 studies (45%) evaluated NPs and 16 (55%) studied MBPs. Level II reproducible evidence supports use of arnica to decrease postoperative edema after rhinoplasty, onion extract to improve scar pigmentation, hypnosis to alleviate perioperative anxiety, and acupuncture to improve perioperative nausea. Level Vevidence reports on the risk of bleeding in gingko and kelp use and the risk of infection in acupuncture use. After year 2000, 92% of NP studies versus 44% of MBP studies were published (P = 0.008). Conclusions: High-level evidence studies demonstrate promising results for the use of both NPs and MBPs in the care of plastic surgery patients. Further study in this field is warranted.

show abstract

Herbal Products That May Contribute to Hypertension

Abstract: This study lists the herbal products that may cause hypertension and should be considered when a patient undergoes plastic surgery to reduce perioperative morbidity related to the herbal supplements.

Cited by 30 publications

References 24 publications

Systemic Hypertension Induced by Harpagophytum procumbens (devil's claw): A Case Report

Systemic Hypertension Induced by Harpagophytum procumbens (devil's claw): A Case Report

Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway

Integrative Medicine in Plastic Surgery

Contact Info

Product

Resources

About