Herbal medicine commonly used against non-communicable diseases in the tropical island of Mauritius

Chintamunnee, Vedamrita; Mahomoodally, Mohamad Fawzi

doi:10.1016/j.hermed.2012.06.001

Cited by 97 publications

(55 citation statements)

References 33 publications

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“…Ethno-Medicinal studies of plants with therapeutic properties are very beneficial for the discovery of modern remedies (Cox, Balick, 1994;Bitu et al, 2015;Baydoun et al, 2015;Heinrich, Gibbons, 2001;Kpodar et al, 2015;Samoisy, Mahomoodally, 2015;Tchouya et al, 2015). According to the World Health Organization (WHO), about 4 billion people in developing countries not only trust in the therapeutic properties of medicinal plant but also use them consistently (Rai, Prasad, Sharma, 2000;Chintamunnee, Fawzi Mahomoodally, 2012;Yavuz et al, 2015). Among developing countries, Iran is a vast country of rich plant resources including considerable number of medicinal plants (Mosaddegh et al, 2012;Jafarirad, Damanafshan, 2017) (Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Pharmaceutical ethnobotany in the Mahabad (West Azerbaijan) biosphere reserve: ethno-pharmaceutical formulations, nutraceutical uses and quantitative aspects

Jafarirad

Rasoulpour

2019

Braz. J. Pharm. Sci.

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This study endeavors to overcome the limits of an orally transmitted pharmacopoeia, and tries to utilize the large ethnobotany patrimony of the area to investigate the biological diversity. Thirty-five traditional practitioners from dissimilar ethnic groups including traditional health practitioners (THPs) and indigenous people were interviewed. A total of 35 species of plants, belonging to 20 families were recognized for the treatment of more than 26 types of ailments. Informant consensus factor (FIC) values of this study reflected the high agreement in the use of plants in the treatment of gastro-intestinal complaints, infectious, parasitic diseases and constipation among the informants. Constipation had the highest use-reports and 8 species of plants had the highest fidelity level (FL) of 100%. In addition one of the species showed the highest relative importance (RI) value of 2.00. Priority should be given to phytochemical investigation of plants that scored the highest FL, FIC, RI values; as such values could be considered as a good indicator of potential plants for discovering new drugs. In addition, traditional knowledge of THPs should be taken into consideration in order to smooth continuation and extension of the nutraceutical aspects and biological diversity of the region.

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Section: Introductionmentioning

confidence: 99%

Pharmaceutical ethnobotany in the Mahabad (West Azerbaijan) biosphere reserve: ethno-pharmaceutical formulations, nutraceutical uses and quantitative aspects

Jafarirad

Rasoulpour

2019

Braz. J. Pharm. Sci.

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“…In rural areas of developing countries, they continue to be used as the primary source(s) of medicine [7]. About 80% of the people in developing countries are reported to use traditional medicines for their health care and as such renewed interest in plant medicine, is been developed by a lot of scientists and conscious efforts are now directed at the screening of medicinal plants with a view of screening secondary metabolites and mineral that will serve as templates for the total synthesis of compounds with enhanced similar structure activity relationship [6] [17]. Phytochemicals are biologically active, naturally occurring chemical compounds found in plants, which provide health benefits for humans.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical, antimicrobial and nutritional properties of Morinda lucida benth and Nauclea latifolia leaf extracts

Enabulele¹,

Amusa²,

Uwadiae³

2017

Int. J. Sci. World

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The leaves of two medicinal plants namely; Morinda lucida and Nauclea latifolia were investigated for their antibacterial, mineral and phytochemical properties. Results of the study showed that the aqueous and ethanolic extract of the two leaves had significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Listeria monocytogenes and Proteus mirabilis. The biologically active constituents present in the extracts were cardiac glycosides, tannins, saponin, coumarins, reducing sugar, terpenoids, alkaloids, steroids and flavonoids. The percentage yield extracts of the respective plants were Morinda lucida leaves 12.9% for ethanol and 9.0% for aqueous extracts while Nauclea latifolia had 12.1% for ethanol and 8.4% for aqueous extracts. Results of the antibacterial activity analysis revealed that the ethanolic extracts of the two medicinal plants at different concentrations were more active against the test organisms named above than the aqueous extracts. The MIC values for the ethanolic extracts ranged between 25.0 and 100.0 mg/ml while that of aqueous extract ranged between 50.0 and 100.0 mg/ml. The MBC values for ethanolic extract ranged between 50.0 and 100mg/ml while that of aqueous extracts also ranged between 50.0 and 100mg/ml. Analysis of the mineral content of the plant leaves shows that they were rich in potassium and calcium. This study confirms that the leaf extracts have some reasonable level of antimicrobial activity and appreciable amounts of mineral content which could be beneficial to human health. The findings from this work can be further exploited for isolation and characterization of novel Phytochemical compounds which could be used in the treatment of infectious diseases especially in light of the emergence of drug-resistant microorganisms and the need to produce new effective antimicrobial agents.

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“…Herbal medicines include herbs, herbal materials, herbal preparations, and finished herbal products that contain parts of plants or other plant materials as active ingredients. 12 Medicinal plants, unlike pharmacological drugs, commonly contain several chemicals working together catalytically and synergistically since they possess different phytochemicals, that is, secondary metabolites, that produce a combined effect that surpasses the total activity of the individual constituents. [13][14] So also, due to synergistic effects, medicinal plants are reported to be more biologically active than their purified constituents.…”

Section: Introductionmentioning

confidence: 99%

Gas Chromatography - Mass Spectrometry Analysis and In vitro Antioxidant Activity of the Ethanolic Extract of the Leaves of Tabernaemontana divaricata

Anbukkarasi¹,

Thomas²,

Sundararajan³

et al. 2016

Phcogj

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Objective: To identify phytoconstituents present in an ethanolic extract of the leaves of Tabernaemontana divaricata and to evaluate its in-vitro antioxidant potential. Methods: The extract was subjected to gas chromatography-mass spectrometry analysis to identify phytoconstituents, and screened for hydroxyl, superoxide and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, reducing power and metal-chelating activity as a measure of potential antioxidant activity. Results: GC-MS analysis of the extract revealed the presence of 96 phytoconstituents, of which 17 are reported to be bioactive and 11 of these to possess antioxidant potential. When tested in-vitro, the extract exhibited the most potent radical-scavenging activity at a maximum concentration of 10 mg/ml, scavenging effects of 64%, 67% and 69% and corresponding half maximal inhibitory concentration (IC 50 ) values of 6.7 mg/ml, 6.8 mg/ml and 6.2 mg/ml on hydroxyl, superoxide and DPPH radicals, respectively. Ascorbic acid used as a standard (10 mg/ml) showed scavenging effects of 73%, 73% and 75% and corresponding IC 50 values of 5.3 mg/ml, 5.8 mg/ml and 5.2 mg/ml, respectively, on hydroxyl, superoxide and DPPH radicals. At 10 mg/ml, the extract and an ethylenediaminetetraacetic acid standard exhibited 68% and 78%, respectively, chelation of ferrous ions; at the same concentration, the reducing power of the extract and that of a butylated hydroxytoluene standard was found to be 3.855 and 4.308, respectively. Conclusion: These observations strongly suggest that the ethanolic extract of T. divaricata leaves has potent in-vitro antioxidant activity and thereby could act as a possible therapeutic agent for oxidative stressinduced pathological states.

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Herbal medicine commonly used against non-communicable diseases in the tropical island of Mauritius

Cited by 97 publications

References 33 publications

Pharmaceutical ethnobotany in the Mahabad (West Azerbaijan) biosphere reserve: ethno-pharmaceutical formulations, nutraceutical uses and quantitative aspects

Pharmaceutical ethnobotany in the Mahabad (West Azerbaijan) biosphere reserve: ethno-pharmaceutical formulations, nutraceutical uses and quantitative aspects

Phytochemical, antimicrobial and nutritional properties of Morinda lucida benth and Nauclea latifolia leaf extracts

Gas Chromatography - Mass Spectrometry Analysis and In vitro Antioxidant Activity of the Ethanolic Extract of the Leaves of Tabernaemontana divaricata

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