Hepatorenal Index as an Accurate, Simple, and Effective Tool in Screening for Steatosis

Marshall, Richard H.; Eissa, Marna; Bluth, Edward I.; Gulotta, P.; Davis, Nancy K.

doi:10.2214/ajr.11.6677

Cited by 105 publications

(141 citation statements)

References 34 publications

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“…Penelitian yang dilakukan oleh Marshall dkk. 19 dan Soder dkk. 20 melaporkan bahwa perhitungan indeks hepatorenal mempergunakan program software ImageJ merupakan metode yang sederhana, terpercaya, dan mudah diakses dengan biaya yang terjangkau untuk mengevaluasi perlemakan hati nonalkoholik.…”

Section: Pendahuluanunclassified

Hubungan Stadium Hipertensi dengan Derajat Perlemakan Menggunakan Indeks Hepatorenal Sonografi

Marina

Nugraha

Santiana

et al. 2017

GMHC

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AbstrakHipertensi merupakan prekursor perkembangan perlemakan hati nonalkoholik. Modalitas pencitraan USG paling banyak digunakan untuk menegakkan diagnosis perlemakan hati nonalkoholik. Saat ini dikembangkan teknik USG menggunakan parameter indeks hepatorenal sonografi yang dihitung dengan program software ImageJ dan digunakan untuk memprediksi derajat perlemakan hati. Penelitian ini bertujuan mengetahui hubungan antara stadium hipertensi dan derajat perlemakan hati nonalkoholik menggunakan indeks hepatorenal sonografi. Penelitian menggunakan studi observasional analitik dengan rancangan cross sectional, pengambilan sampel dilakukan secara consecutive admission. Penelitian dilaksanakan di Bagian Radiologi RSUP Dr. Hasan Sadikin Bandung periode Juni-Agustus 2016. Subjek penelitian 50 orang, laki-laki 22 orang, perempuan 28 orang, usia termuda 25 tahun, dan tertua 77 tahun. Hasil penelitian melalui uji statistik chi-square menunjukkan derajat perlemakan hati nonalkoholik ringan lebih banyak pada prehipertensi (9 dari 16), derajat sedang pada hipertensi stadium I (10 dari 19), dan derajat berat pada hipertensi stadium II (8 dari 15) dengan p<0,001. Perlemakan hati nonalkoholik derajat sedang dan berat lebih sering ditemukan pada perempuan dengan hipertensi (p=0,005) Simpulan, terdapat hubungan antara stadium hipertensi dan derajat perlemakan hati nonalkoholik menggunakan indeks hepatorenal sonografi. Kata kunci: ImageJ, indeks hepatorenal sonografi, perlemakan hati nonalkoholik, stadium hipertensi, USG The Association of Hypertension Stage and Non-Alcoholic Fatty Liver Degree Using Hepatorenal Sonography Index AbstractHypertension is considered as a precursor to the development of non-alcoholic fatty liver disease (NAFLD). Ultrasonography techniques have been developed using sonography hepatorenal index parameter calculated by ImageJ, that can predict the degree of NAFLD. This study aim to determine the relationship between hypertension stage and the degree of NAFLD using sonography hepatorenal index. The research is an observational using cross sectional methods, with consecutive admission sampling method. The study was performed at Dr. Hasan Sadikin Hospital Bandung from June to August 2016. A total of 50 subjects, 22 men and 28 women, with the youngest 25 and the oldest 77 years old participated. Results indicated that the mild degree of NAFLD were higher on prehypertension (9 of 16), the moderate degree on stage I hypertension (10 of 19), while the severe degree found on stage II hypertension (8 of 15), with p<0.001. Moderate and severe degree of NAFLD in hypertensive patient was more common in women (p=0.005). In conclusion, there is a relationship between hypertension stage and the degree of NAFLD.

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Section: Pendahuluanunclassified

Hubungan Stadium Hipertensi dengan Derajat Perlemakan Menggunakan Indeks Hepatorenal Sonografi

Marina

Nugraha

Santiana

et al. 2017

GMHC

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“…In addition, point estimates of SHRI for the prediction of steatosis grades less than moderate or severe appear to be superior to those of qualitative grading methods [29]. The sensitivity and specificity of SHRI varied in some studies between 93-100% and 54-93% respectively [61][62][63].…”

Section: Optimization Of the Usual Ultrasonographic Examination Throumentioning

confidence: 99%

Noninvasive assessment of liver steatosis using ultrasound methods

2014

Med Ultrason

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Hepatic steatosis is a condition frequently encountered in clinical practice, with potential progression towards chirrhosis and hepatocellular carcinoma. Ultrasonography (US) is one of the noninvasive imaging techniques used in the diagnosis of steatosis. We will review the US diagnostic criteria, the US performance in the diagnosis and grading of hepatic steatosis, the US steatosis models, but also its limitations in the diagnosis of steatosis. In addition, we will discuss 2 modern methods of assessing hepatic steatosis using ultrasounds, namely the computerized processing of data forming the US image and the controlled attenuation parameter measured with unidimensional transient elastography.

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“…Usually, US for the diagnosis of NAFLD is based mainly on a subjective assessment of liver echogenicity [7][8][9]. However, this method is operator-dependent with high inter-and intraobserver variability [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Noninvasive quantitative estimation of hepatic steatosis by ultrasound: a comparison of the hepato-renal index and ultrasound attenuation index.

et al. 2016

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Aims: To compare the accuracy of the ultrasound attenuation index (USAI) and hepato-renal index (HRI) for the diagnosis of hepatic steatosis (HS). Material and methods: Two hundred and twenty-four potential living hepatic donors underwent US and subsequent US-guided liver biopsy. The USAI was calculated from US images with an 8 MHz transducer and HRI was measured on sagittal images with a clear visualization of both the liver and kidney. Using histological degrees of HS as the reference standard, we compared the performance of USAI and HRI for diagnosing HS ≥ 5% and ≥ 30% by receiver operating characteristic curve analysis. The interobserver agreement was evaluated by using intraclass correlation coefficients (ICCs) or Bland–Altman statistics. Results: Histologic degree of HS was 0–70% (median, 5%). HRI showed a tendency towards higher accuracy than USAI for diagnosing HS ≥ 5% (the area under the ROC curve, 0.856 vs. 0.820; p= 0.279) and ≥ 30% (0.937 vs. 0.909; p = 0.378) without statistical significance. There was an excellent interobserver agreement for both USAI and HRI (ICC = 0.931 and 0.973, respectively). According to the Bland–Altman method, the 95% limits of difference between two readers for HS were −8.5% to 6.6% by USAI and −4.8% to 6.2% by HRI. Most patients would have the difference of calculated HS by USAI (74.0%) and HRI (96.0%) from different operators within a range of ±5%. Conclusions: Although statistically insignificant, HRI was superior to USAI for the diagnosis and quantitative estimation of HS in terms of diagnostic performance, including accuracy and reproducibility.

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Hepatorenal Index as an Accurate, Simple, and Effective Tool in Screening for Steatosis

Abstract: The hepatorenal index is a simple, reliable, and cost-effective screening tool for identifying patients who should not undergo liver biopsy for evaluation of steatosis.

Cited by 105 publications

References 34 publications

Hubungan Stadium Hipertensi dengan Derajat Perlemakan Menggunakan Indeks Hepatorenal Sonografi

Hubungan Stadium Hipertensi dengan Derajat Perlemakan Menggunakan Indeks Hepatorenal Sonografi

Noninvasive assessment of liver steatosis using ultrasound methods

Noninvasive quantitative estimation of hepatic steatosis by ultrasound: a comparison of the hepato-renal index and ultrasound attenuation index.

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