Hepatoprotective and Antioxidant Activity of &lt;i&gt;Lannea coromandelica&lt;/i&gt; Linn. on Thioacetamide Induced Hepatotoxicity in Rats

Rao, V. Srinivasa; Einstein, John Wilking; Das, Kuntal Kanti

doi:10.56431/p-ha9scc

Cited by 2 publications

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“…The biological properties of L. coromandelica are numerous ( Table 5 ). A stem bark extract has shown in vitro antimicrobial, hypotensive, and sporicidal activities [ 68 ]; studies on the bark revealed in vivo anti-diarrhoeal activity and in vitro antimicrobial activities [ 69 , 70 , 71 ]; the presence in stem bark of dihydroflavonols and terpenoids, polyphenols, flavonoids, kaempferol, and quercetin provided in vivo hepatoprotective and antioxidant activities to this medicinal plant [ 72 ].…”

Section: Resultsmentioning

confidence: 99%

Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review

Malú,

Caldeira,

Catarino

et al. 2024

Plants

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Lannea L. genus belongs to the Anacardiaceae botanical family and has long been used in traditional medicinal systems of many countries to manage several health conditions, but no studies have been conducted regarding its usefulness as a source of herbal medicine for human use. A literature review was conducted on scientific papers indexed on B-On, Pubmed, and Web of Science databases. Our results showed that medicinal plants from this botanical genus, mostly constituted by bark and leaf, are often used to approach a wide variety of disease symptoms, like fever, inflammatory states, pain, and gastrointestinal disorders. Phytochemical profiles of Lannea species revealed that phenolic acid derivatives including hydroquinones, phenolic acids, flavonoids, condensed tannins, and triterpenoids are the main classes of secondary metabolites present. Among the total of 165 identified compounds, 57 (34.5%) are flavonoids, mostly quercetin- and myricetin-derived flavonols and catechin and epicatechin flavan-3-ol derivatives also containing a galloyl group. In vitro and in vivo studies allowed the identification of 12 different biological activities, amongst which antimicrobial, antioxidant, anti-inflammatory, and cytotoxic activities were the most frequently cited and observed in in vitro essays. Our review contributes useful information for the scientifical validation of the use of Lannea species in traditional medicinal systems and shows that more research needs to be conducted to better understand the concrete utility of these as herbal medicines.

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Section: Resultsmentioning

confidence: 99%

Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review

Malú,

Caldeira,

Catarino

et al. 2024

Plants

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show abstract

“…Contusions, inflammatory diseases, chronic gastritis, canker sores, scars, skin rash, and other conditions are treated with the bark. Traditional applications, as well as the abovementioned pharmacological findings, support the plant's therapeutic potency [36,37].…”

Section: Introductionmentioning

confidence: 99%

Phytochemistry and Pharmacological Bio-Activities of Lannea Coromandelica: A Review

2022

Innovare J Med Sci

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Lannea coromandelica is extensively employed as a medicinal herb across the globe. This research work focuses primarily on the phytochemistry, pharmaceutics, and bio-exertion of L. coromandelica. In ethnomedicine, several members of this species function as astringents, aiding in anti-oxidant, anti-inflammatory, and anti-diabetic and are helpful in other physiological functions. In addition, Lannea species’ therapeutic benefits were acknowledged in numerous scientific investigations. The conclusions derived from the current study corroborate that the therapeutic activities of L. coromandelica can be linked to the presence of a broad spectrum of secondary metabolites and bioactive phytocompounds such as phenols, flavonoids, tannins, and proteins, according to the current study. This review highlights phyto-assembly and phyto-activities such as a diuretic, cardiovascular, and bioactivities such as antiepileptic, antimicrobial, and anti-convulsant, and pharmaceutical activities such as anti-cancer, anti-diabetic, and anti-asthmatic properties.

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Hepatoprotective and Antioxidant Activity of <i>Lannea coromandelica</i> Linn. on Thioacetamide Induced Hepatotoxicity in Rats

Cited by 2 publications

References 0 publications

Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review

Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review

Phytochemistry and Pharmacological Bio-Activities of Lannea Coromandelica: A Review

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