Abstract:BACKGROUNDS-Adenosyl-L-Methionine (SAM) protects liver cells in viral hepatitis and paracetamol-induced hepatic damage, etc. But, there are scanty data regarding hepatoprotective effect of SAM in isoniazid-induced liver damage. With this background, the present study is undertaken to assess the activity of SAM in isoniazid-induced liver damage in animal model.
MATERIALS AND METHODSHepatic injury was induced in albino rats by administering isoniazid (INH) at a dose of 54 mg/kg orally once daily for 30 days and … Show more
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