Hepatitis C screening and referral for further investigation and treatment in a tertiary care hospital

İskender, Gülşen; Mert, Duygu; Çeken, Sabahat; Bahçecitapar, Melike; Yenigün, Ayla; Ertek, Mustafa

doi:10.3855/jidc.12584

Cited by 5 publications

(8 citation statements)

References 16 publications

(22 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When we investigated the patient group (31.2%) who were anti-HCV positive without HCV RNA testing, we found that the percentage of overlooking HCV RNA was high in the internal and surgery departments according to the infection department. In a study similar to ours, Gulsen et al have revealed that the awareness of surgeons and other clinicians about HCV was low [7]. The physician awareness should be increased by adding the cautions and information about HCV diagnosis and treatment to the hospital computer program [22].…”

Section: Discussionsupporting

confidence: 57%

“…There are highly effective direct acting antiviral drugs that are now available to cure HCV. The screening of HCV infection is important to identify and to treat individuals with active infection [6,7].…”

Section: Discussionmentioning

confidence: 99%

“…Potent diagnostic approaches are necessary in order to increase early detection of HCV infection. The patients of HCV infected could be reach by using screening programme data and electronic health records [7].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of patients whose HCV serology was investigated in our hospital between 2010-2018

Tünay¹,

Demirtürk²

2022

Med-Science

View full text Add to dashboard Cite

HCV infection is commonly asymptomatic, most people infected with HCV are not aware that they are infected, and most of those who receive a diagnosis also currently cannot reach treatment. Our study, it was aimed to appreciate the rate of anti-HCV-positive patients and the awareness and knowledge of patients about their hepatitis C follow-up or treatment. In this study, we evaluated 56.115 patients who were screened for anti-HCV tests retrospectively. The patients who have positive HCV RNA tests with anti-HCV tests and without having HCV RNA test results were attempted to reach by phone. Anti-HCV positivity was determined in 708 (1.3%) patients. The mean age of 708 patients (Female, n=415;58.6%, and male, n=293;41.4%) was 63 years. Anti-HCV was positive in 708 patients, HCV RNA test was positive in 324 (45.8%) patients and negative in 163 (23.0%) patients. In 221 (31.2%) patients with positive of anti-HCV tests. The distribution rates of the requesting HCV RNA test in departments were: 41.8% in the infectious department, 39.4% in the internal department, 18.8% in the surgery department. Among 324 patients, 65 of them were phoned. Among 65 patients, 14 of them were being treated in another center, 11 of them were treated in our hospital. Among 221 patients who were not tested for HCV RNA 74 of them were phoned. Among 74 patients, 16 of them were being treated in another center and 7 of them were treated in our hospital. We found that the knowledge of physicians about HCV screening and treatment is low in the eradication of HCV. This situation emerged as the most important limitation of the study. Therefore, education programs about the notification of the HCV cases to the doctors for diagnosis and treatment may be beneficial.

show abstract

Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of patients whose HCV serology was investigated in our hospital between 2010-2018

Tünay¹,

Demirtürk²

2022

Med-Science

View full text Add to dashboard Cite

show abstract

“…At the same time, many healthcare workers lack awareness of further management of antibody positive individuals, particularly in some developing countries, primary care facilities and non-specialist departments. Data from a tertiary hospital in Turkey revealed, in anti-HCV positive patients, HCV RNA testing was requested least by surgery and other clinics (21 and 25% respectively), while most by infectious disease (100%) and gastroenterology (70.58%) clinics ( 6 ). In addition, although hepatitis C screening rates are high in hospitals, further diagnosis, referral and treatment rates are low, which is not uncommon in developed countries.…”

Section: In-hospital Hepatitis C Screeningmentioning

confidence: 99%

“…other clinics (21 and 25% respectively), while most by infectious disease (100%) and gastroenterology (70.58%) clinics (6). In addition, although hepatitis C screening rates are high in hospitals, further diagnosis, referral and treatment rates are low, which is not uncommon in developed countries.…”

Section: High-income Countriesmentioning

confidence: 99%

Management of in- and out-of-hospital screening for hepatitis C

Zhou

Wang

et al. 2023

Front. Public Health

View full text Add to dashboard Cite

Because of insidious progression and no significant clinical symptoms at early stage, chronic hepatitis C (CHC) is often diagnosed after the occurrence of cirrhosis and hepatocellular carcinoma. Highly effective and low drug resistance of direct-acting antiviral agents (DAAs) have enabled cure of CHC, encouraging the World Health Organization to propose a global viral hepatitis elimination program. To Date, vaccine for CHC is still under research. Therefore, reducing the source of infection is an important means of eliminating CHC other than cutting off the transmission route, which requires screening, diagnosing and treating as many patients in the population as possible. Hospital-based screening strategy have been found to be cost-effective in the management of CHC screening, as reported both nationally and internationally. Currently, China has issued In-hospital process for viral hepatitis C screening and management in China (Draft) in April, 2021, which provides a standardized implementation process and direction for in-hospital hepatitis C screening and treatment, but still requires medical institution to develop its own management process, taking into account its current situation and learning from domestic and international experience. In addition, screening for CHC outside the hospital among special populations, such as blood donors, pregnant women, homosexuals, intravenous drug users, prisoners, and residents in rural areas with scarce medical care resources, also requires attention and development of targeted and rational screening strategies. In this paper, we analyze and recommend the management of hepatitis C screening from both in-hospital and out-of-hospital perspectives, with the aim of contributing to the formulation of hepatitis C screening strategies.

show abstract

Treatment initiation rates of patients with positive anti-hepatitis C virus results in tertiary hospitals in Turkey: a retrospective, cross-sectional chart review (Lost-C Study)

Çelen

Şengel

Kaya

et al. 2022

Preprint

View full text Add to dashboard Cite

Background: The aim of this national, multicenter, cross-sectional, retrospective chart review study was to determine the rate of patients in Turkey who received hepatitis C virus (HCV) treatment after receiving positive anti-HCV results during HCV screening. Methods: Data related to patients’ demographics, laboratory results, the time interval from obtaining a positive anti-HCV result to treatment initiation, the specialty of the physician requesting anti-HCV screening, and type of hospital were collected and analyzed. Results: Among 1000 patients who received a positive anti-HCV result, 50.3% were male and 78.5% were screened for HCV-RNA. Among HCV-RNA screened patients, 54.8% (n = 430) had a positive result. Among patients testing positive for HCV-RNA, 72.8% received HCV treatment in line with their positive anti-HCV results. The median time from obtaining a positive anti-HCV result to initiation of HCV treatment was 91.0 days (interquartile range 42.0 to 178.5). Non-surgical branches requested HCV-RNA testing more frequently than surgical branches (p < 0.001). The rate of access to HCV treatment was higher in patients screened in university hospitals than in patients screened in training and research hospitals (p < 0.001). Conclusions: Our results indicate a higher rate of treatment initiation in patients with HCV infection than is described in the published literature. Furthermore, the time from screening to treatment initiation was considerably shorter compared with other international studies. However, because HCV-RNA testing was not requested in a significant portion of patients with a positive test result for anti-HCV, there might be a large patient population with HCV who do not receive treatment.

show abstract

Hepatitis C screening and referral for further investigation and treatment in a tertiary care hospital

Cited by 5 publications

References 16 publications

Evaluation of patients whose HCV serology was investigated in our hospital between 2010-2018

Evaluation of patients whose HCV serology was investigated in our hospital between 2010-2018

Management of in- and out-of-hospital screening for hepatitis C

Treatment initiation rates of patients with positive anti-hepatitis C virus results in tertiary hospitals in Turkey: a retrospective, cross-sectional chart review (Lost-C Study)

Contact Info

Product

Resources

About