Hepatic Visceral Larva Migrans of <i>Toxocara canis</i>: CT and Sonographic Findings

Chang, Sun O; Lim, Jae Hoon; Choi, Dongil; Park, Cheol Keun; Kwon, Namhee; Cho, Seung Yull; Choi, Dong-Chull

doi:10.2214/ajr.05.1416

Cited by 76 publications

(69 citation statements)

References 30 publications

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“…Among the visceral organs involved, the liver is the most commonly affected due to the portal venous drainage (Graeff-Teixeira et al, 2009). VLM syndrome has a worldwide prevalence, although there is a strong prediction for the tropical countries (Chang et al, 2006). The rate of infection is higher in developing countries, but highly under reported due to diffi culties in fi nding the parasites in the tissues.…”

Section: Discussionmentioning

confidence: 99%

Human case of visceral larva migrans syndrome: pulmonary and hepatic involvement

Almatary

Bakir

2016

Helminthologia

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SummaryVisceral Larva Migrans (VLM) syndrome is commonly caused by larvae of roundworms Toxocara canis or Toxocara cati. Human toxocarosis is a soil-transmitted zoonosis, which may result in partial or general pathological changes in host tissues. We reported a case of 14-year-old boy presented with severe dry cough without dyspnea, mild chest and abdominal pain with general fatigue. Examination of peripheral blood showed marked increase in eosinophils. The chest radiography showed an infi ltrative shadow in the lung fi elds. Chest CT demonstrated multiple opacities in both lungs. Abdominal CT showed multiple low attenuation areas in the liver. Ultrasound guided liver biopsy revealed granulomas with severe eosinophilic infi ltration. The boy was treated with albendazole and responded radically. It is worth mentioning that this is the fi rst case of hepato-pulmonary VLM syndrome in Egypt.

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Section: Discussionmentioning

confidence: 99%

Human case of visceral larva migrans syndrome: pulmonary and hepatic involvement

Almatary

Bakir

2016

Helminthologia

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“…Assim como em adultos, essa relação mantém-se até três vezes maior no sexo masculino em relação ao sexo feminino 59 . Entretanto, em vários estudos, não houve diferença estatística entre o sexo masculino e o feminino em pacientes com toxocaríase 16,20,[29][30][31][32][33]35,36,44,55 .…”

Section: Epidemiologiaunclassified

“…101 e lesões hepáticas múltiplas 59,102 , assim com relato de três casos de crianças com granulomas hepáticos ao ultrassom abdominal 58 .…”

Section: Comprometimento Visceral De Outros Sistemasunclassified

“…Muitos casos de pacientes relatados na literatura com sorologia positiva e sintomas compatíveis com toxocaríase não apresentaram eosinofilia 26,69,83,86,94,112,120 . Na literatura, há vários casos de toxocaríase com presença de eosinofilia 1,2,22,25,28,53,59,67,77,121,122 . Glickman et al 97 observaram que pacientes com presença de IgE elevada e eosinófilos no sangue periférico acima de 400 células/ mm 3 apresentavam 82% de probabilidade de desenvolver toxocaríase.…”

Section: Diagnósticounclassified

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Toxocariasis: visceral larva migrans in children

Carvalho¹,

Rocha²

2011

J Pediatr (Rio J)

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Objectives: To present a detailed investigation of risk factors, symptoms, and laboratory and imaging tests that may be useful to establish the clinical laboratory diagnosis of visceral larva migrans (VLM) in children, demonstrating the importance of diagnosis and treatment to prevent complications in the eyes, liver, and other organs. Sources:Literature review using the MEDLINE and LILACS (1952-2009) databases, selecting the most recent and representative articles on the topic. Summary of the findings:VLM is an infectious disease with nonspecific clinical presentation, whose transmission is related to contact with dogs, especially puppies, and which may progress to late systemic complications in vital organs such as the eyes and the central nervous system. IgG (ELISA) anti-T. canis can be used to establish the laboratory diagnosis. Higher cutoff points suggest recent illness and lower cutoff points demonstrate mild infection or infection in remission. Therapeutic response may be assessed by means of eosinophil blood cell count. The present article provides the pediatrician with updated information regarding VLM, a disease of high prevalence worldwide and in Brazil. Conclusions:The diagnosis of VLM depends mainly on the presence of dogs in the child's household, associated with ELISA (IgG anti-T. canis), using excretory-secretory antigens of Toxocara canis. Prospective studies are warranted to assess the best drug therapy. Prevention is the most important strategy because of the high prevalence of T. canis in urban areas.J Pediatr (Rio J). 2011;87(2):100-110: Toxocara canis, dogs, infection, epidemiology, ELISA, prevalence. ResumoObjetivos: Apresentar investigação detalhada de fatores de risco, sintomatologia, exames laboratoriais e de imagem que possam contribuir para o diagnóstico clínico-laboratorial da larva migrans visceral (LMV) em crianças e mostrar a importância do diagnóstico e do tratamento para evitar complicações oculares, hepáticas e em outros órgãos. Fontes dos dados:Revisão de literatura utilizando os bancos de dados MEDLINE e LILACS , selecionando os artigos mais atuais e representativos do tema. Síntese dos dados:LMV é uma doença infecciosa de apresentação clínica inespecífica cuja transmissão está relacionada ao contato com cães, principalmente filhotes, podendo evoluir com complicações sistêmicas tardias em órgãos vitais como o olho e sistema nervoso central. Para diagnóstico laboratorial, pode ser utilizado IgG (ELISA) anti-Toxocara canis, cujos pontos de corte mais elevados sugerem doença recente e, os mais baixos, infecção leve ou em resolução. A resposta terapêutica pode ser avaliada por meio da contagem de eosinófilos no sangue. Esse artigo atualiza o pediatra em relação à LMV, doença de alta prevalência no mundo e no Brasil.Conclusões: O diagnóstico de LMV depende principalmente da epidemiologia da presença de cães no domicílio da criança, associada ao ELISA (IgG para T. canis), utilizando antígenos Toxocara de excreção e secreção. São necessários estudos prospectivos para avali...

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“…VLM secondary to T. canis is primarily a disease of children who live in poor sanitary conditions, and are likely to ingest contaminated soil containing T. canis eggs deposited by dogs infested with the parasite (3). The most common route of infection in adult humans, however, is through ingestion of raw liver from a cow (4). Regardless of the source, the eggs are swallowed and hatched in the intestine.…”

Section: Discussionmentioning

confidence: 99%

Hepatic Toxocariasis with Atypical CT and MR Imaging Findings: a Case Report

Shin

Lee

et al. 2018

Investig Magn Reson Imaging

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Hepatic toxocariasis is a type of visceral larva migrans caused by the migration of second-stage larvae of certain nematodes such as Toxocara canis to the liver. Histologically, the condition is characterized by granulomatous lesions containing eosinophils and inflammatory cells. We report a case of hepatic toxocariasis with atypical clinical and radiologic findings presenting as distinct, solitary hepatic nodule detected in a middle-aged woman.

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Hepatic Visceral Larva Migrans of Toxocara canis: CT and Sonographic Findings

Abstract: CT and sonographic findings of hepatic visceral larva migrans of T. canis are multiple, ill-defined, oval or elongated, small, nodular lesions scattered in the liver parenchyma. The presence of hepatic lesions on images was associated with higher peripheral eosinophil count and percentage.

Cited by 76 publications

References 30 publications

Human case of visceral larva migrans syndrome: pulmonary and hepatic involvement

Human case of visceral larva migrans syndrome: pulmonary and hepatic involvement

Toxocariasis: visceral larva migrans in children

Hepatic Toxocariasis with Atypical CT and MR Imaging Findings: a Case Report

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