Hepatic Veno-Occlusive Disease in a Renal Transplant Patient Receiving Azathioprine

Azathioprine in dermatology: The past, the present, and the future

“…263 Hepatic veno-occlusive disease has also been reported and is found most often in patients with nondermatologic diseases, mostly renal transplantation patients or patients with gastroenterologic disorders. [266][267][268][269][270][271][272] Malignancy potential…”

Portal hypertension secondary to azathioprine in myasthenia gravis

“…He underwent thymectomy and 3 months later was started on prednisolone, which was tapered to a maintenance dose of 20mg on alternate days. Due to continuing weakness he was started on azathioprine 150 mg daily, 6 Over the next 2 years his myasthenia improved and he remained in good general health. His MCV rose to 115 fl and platelet count fell to 110 x 109/1.…”

Budd-Chiari Syndrome: Some Pathologic-Anatomic Aspects

“…[30][31][32] The major hepatic veins usually remain free from inflammatory changes, but combinations of the radicular and the truncular forms have been reported.33,34 Etiologically charges have been brought especially against chronic intoxication by pyrrolizine-alkaloids from certian senecio, crotalaria and heliotrope species -plants which exist for example in South Africa, in the Far East and in Jamaica.26.3O-32,35 Similar changes of the small hepatic veins have also been described after radiation therapy, after immunosuppressive treatment and after bone marrow transplantation. [36][37][38][39][40][41][42] Therapy and Prognosis As causal therapy is only possible in a few cases, the prognosis with the Budd-Chiari syndrome must still be considered, even now, as decidedly poor. If a congenital membrane of the inferior vena cava is present, transatrial severance can be tried as causal therapy.…”