Hepatic small vessel neoplasm case report: A surveillance conundrum

Hepatic small vessel neoplasm – A systematic review

“…In addition to the 17 cases described by Gill et al, a further six more cases have been reported in five other articles, thus bringing the total number to 23 [ 1 , 7 , [10] , [11] , [12] , [13] ] (See Table 1 .).…”

“… e Lewis [ 11 ]. f Mulholland [ 1 ]. g The pathologic interpretation of c-myc and p53 is reported in several ways in the literature, where a normal pattern of staining can be recorded as either “weak” or “negative”; this distinction is not important as long as it is not strongly positive, which can be seen in angiosarcoma.…”

“…Reported follow-up amongst the patients was variable, the shortest being one month and the longest being 24 months, with a mean of seven months. Six patients had positive margins or residual disease, of which the longest follow-up was 14 months with no reported evidence of disease recurrence [ 1 ]. The remaining 18 patients had no residual disease.…”

“…Since the initial description by Gill et al, six additional cases of HSVN have been reported [ 1 , 7 , [10] , [11] , [12] , [13] ], giving a total of 23 cases. It is possible lesions recently described as “anastomosing haemangioma” of the liver also represent HSVN [ [17] , [18] , [19] ], however on discussion this was excluded as its description was not completely typical of HSVN given the infiltrative nature of HSVN as described by Gill et al [ 7 ].…”

“…They can range in size and may potentially give rise to mechanical symptoms due to large size. Four cases presented as multiple lesions [ 1 , 7 ] and it is uncertain if these were synchronous lesions or metastatic disease.…”