Hepatic schistosomiasis japonica identified by CT.

Araki, Tsutomu; Hayakawa, Katsuyuki; Okada, J; Hayashi, Seiko; Uchiyama, Guio; Yamada, Kazutaka

doi:10.1148/radiology.157.3.3933049

Cited by 42 publications

(15 citation statements)

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“…This lesion is thought to be due to septal calcification of schistosomal ova. 60 In the diagnosis of hepatosplenic schistosomiasis using MRI, the most frequent findings are accentuation of periportal signal in T2-weighted sequences, and a hypointense signal in relation to the normal liver parenchyma in T1-weighted sequences with fat suppression. The periportal signal is accentuated on T1-weighted sequences following contrast administration.…”

Section: Diagnostic Imagingmentioning

confidence: 99%

The chronic enteropathogenic disease schistosomiasis

Olveda¹,

Olveda

McManus

et al. 2014

International Journal of Infectious Diseases

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Schistosomiasis is a chronic enteropathogenic disease caused by blood flukes of the genus Schistosoma. The disease afflicts approximately 240 million individuals globally, causing approximately 70 million disability-adjusted life years lost. Chronic infections with morbidity and mortality occur as a result of granuloma formation in the intestine, liver, or in the case of Schistosoma haematobium, the bladder. Various methods are utilized to diagnose and evaluate liver fibrosis due to schistosomiasis. Liver biopsy is still considered the gold standard, but it is invasive. Diagnostic imaging has proven to be an invaluable method in assessing hepatic morbidity in the hospital setting, but has practical limitations in the field. The potential of non-invasive biological markers, serum antibodies, cytokines, and circulating host microRNAs to diagnose hepatic fibrosis is presently undergoing evaluation. This review provides an update on the recent advances made with respect to gastrointestinal disease associated with chronic schistosomiasis.

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Section: Diagnostic Imagingmentioning

confidence: 99%

The chronic enteropathogenic disease schistosomiasis

Olveda¹,

Olveda

McManus

et al. 2014

International Journal of Infectious Diseases

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“…Typical findings of schistosomiasis on US and CT are a network pattern, high-density bands and spotty or linear high-density lesions in the liver associated with calcification of deposited eggs, as seen in this case. 4,5 Laparoscopy showed typical findings; that is, multiple whitish markings and irregular, groove-like septa which are seen in advanced cases. In severe cases, block-like formations separated by groove-like depressions are reported.…”

Section: Discussionmentioning

confidence: 97%

Schistosomiasis Japonica Identified by Laparoscopic and Colonoscopic Examination

Hosho¹,

Ikebuchi²,

Ueki³

et al. 2010

Digestive Endoscopy

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A 45-year-old Philippine woman who came from Mindanao Island was admitted to our hospital with a complaint of epigastric discomfort. Abdominal ultrasonography and computed tomography demonstrated a network pattern and linear calcification in the liver. Laparoscopic examination showed numerous yellowish, small speckles over the liver surface. The liver surface was separated into many small blocks by groove-like depressions, demonstrating a so-called tortoise shell pattern. Conventional colonoscopy and narrow-band imaging showed irregular areas of yellowish mucosa, and diminished vascular network and increased irregular microvessels extending from the descending colon to the rectum. Liver biopsy showed many Schistosoma japonicum eggs in Glisson's capsule and colon biopsy showed many S. japonicum eggs in the submucosal layer. These findings established a diagnosis of schistosomiasis japonica. The present case is imported schistosomiasis japonica. Even though new cases have not occurred recently in Japan, we should remain aware of schistosomiasis japonica for patients who came from foreign epidemic areas.

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“…Compared with ultrasound, the CT scan provides accurate diagnosis of ectopic forms of schistosomiasis involving the central nervous system, pulmonary, and other organ sites. The network pattern seen in the liver in schistosomiasis japonica has been delineated by CT as septal calcification [38,39]. The septal calcification of schistosomal ova in S. japonica has been thought to be responsible for the “turtleback” or “tortoiseshell” appearance of the hepatic lesion [39].…”

Section: Computerized Tomographymentioning

confidence: 99%

Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis

Olveda

Lam

et al. 2014

Clin Microbial

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Diagnosis of schistosomiasis is made by demonstration of the parasite ova in stools, urine,and biopsy specimens from affected organs, or presence of antibodies to the different stages of the parasite or antigens circulating in body fluids by serologic techniques. DNA of schistosomes can now also be detected in serum and stool specimens by molecular technique.However, these tests are unable to determine the severity of target organ pathology and resultant complications. Accurate assessment of schistosome-induced morbidities is now made with the use of imaging techniques like ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). US has made major contributions in the diagnosis of hepatosplenic and urinary form of disease. This imaging method provides real time results, is portable (can be carried to the bed side and the field) and is lower in cost than other imaging techniques. Typical findings in hepatosplenic schistosomiasis by US include: hyperechoic fibrotic bands along the portal vessels (Symmer’s fibrosis), reduction in the size of the right lobe, hypertrophy of the left lobe, splenomegaly, and ascites. More advanced ultrasound equipment like the colour Doppler ultrasound can characterize portal vein perfusion, a procedure that is critical for the prediction of disease prognosis and for treatment options for complicated portal hypertension. Although CT and MRI are more expensive, are hospital based, and require highly additional specially-trained personnel, they provide more accurate description of the pathology, not only in hepatosplenic and urinary forms of schistosomiasis, but also in the diagnosis of ectopic forms of the disease,particularly involving thebrain and spinal cord. MRI demonstrates better tissue differentiation and lack of exposure to ionizing radiation compared with CT.

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Hepatic schistosomiasis japonica identified by CT.

Cited by 42 publications

References 0 publications

The chronic enteropathogenic disease schistosomiasis

The chronic enteropathogenic disease schistosomiasis

Schistosomiasis Japonica Identified by Laparoscopic and Colonoscopic Examination

Utility of Diagnostic Imaging in the Diagnosis and Management of Schistosomiasis

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