Hepatic Histopathological Changes in a Dog with Natural &lt;I&gt;Capillaria hepatica&lt;/i&gt; Infection in Nigeria

Ajayi, O. L.; Omotainse, SO; Antia, RE; Antia, FA; Akande, FA; Olaniyi, MO; Kehinde, O. O.

doi:10.4314/njpar.v31i1.69457

Cited by 3 publications

(1 citation statement)

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“…Hepatic capillariosis was reported in non-human primates (Graczyk et al 1999;Pereira et al 2016) porcupines (Hamir and Rupprecht, 2000) rabbits (Mowat et al 2009) horse (Ochi et al 2017). Canine hepatic capillariosis was reported in India by Patil et al (2017) and worldwide (Landol et al 2003;Palma, 2009;Ajayi et al 2010;de Oliveira et al 2021). Adult humans also suffer from the infection which is manifested as non-speci c symptoms such as persistent fever, hepatomegaly, eosinophilia and sometimes leads to death in humans (Fuehrer et al 2011).…”

Section: Introductionmentioning

confidence: 97%

Canine Hepatic Calodiosis with Cirrhosis

pukkarandi

Hemalatha

Nagarajan

et al. 2022

Preprint

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Parasitic zoonoses from dogs are less frequent although dogs are reservoirs for many zoonotic parasites. The nematode parasite Calodium hepaticum (Capillaria hepatica) has a global distribution and is commonly reported in rodents (definitive host), dogs, cats and wild animals. Humans especially children are more susceptible to the parasitic infection. This paper documents an incidental finding of hepatic calodiosis with cirrhosis in a stray dog and discusses the zoonotic implications. A nondescript dog was brought for necropsy examination to the Department of Veterinary Pathology, Madras Veterinary College, Tamil Nadu, India. Liver appeared dark brown mottled with multifocal random variably sized, grey white flat firm areas. Histopathologically, liver tissue revealed multiple random encysted large collection of eggs surrounded by mild inflammation with a few lymphocytes, macrophages and fine fibrosis. The eggs had characteristic barrel shape, bipolar ends, bilayered wall, cross striations between the walls, and yolk. Periodic acid Schiff stain demonstrated the glycolic wall of ova. Marked portal to portal fibrosis was demonstrated for collagen by Masson’s trichrome and for reticulin by Warthin-Starry stains. The stage of parasitic infection was diagnosed as intermediate to chronic due to fibrosis. A need to study the prevalence of the disease in human and animals and attempts for early diagnosis is emphasized. A caution in general about the zoonotic threat to children/pet parents/ veterinarians/animal handlers caused by C. hepaticum infection which is poorly diagnosed and sporadically reported in India and worldwide.

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Section: Introductionmentioning

confidence: 97%

Canine Hepatic Calodiosis with Cirrhosis

pukkarandi

Hemalatha

Nagarajan

et al. 2022

Preprint

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An overview of the host spectrum and distribution of Calodium hepaticum (syn. Capillaria hepatica): part 2—Mammalia (excluding Muroidea)

Fuehrer

2013

Parasitol Res

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Calodium hepaticum (syn. Capillaria hepatica) is a globally distributed zoonotic nematode with low host specificity and a high affinity to the liver. Although murid rodents are the main definite hosts, various other mammals can be affected with hepatic capillariasis: non-murid rodents, Insectivora, Chiroptera, Lagomorpha, Artiodactyla, Perissodactyla, Hyracoidea, Marsupialia, Carnivora, and Primates. Overall, more than 180 mammalian species (including humans) are known as suitable hosts of this pathogen. This review gives an overview of the distribution and host spectrum of C. hepaticum in non-Muroidean mammals in wildlife and zoos as well as in domesticated and laboratory animals. Furthermore, the role of spurious infections in animals and the dissemination of C. hepaticum by mammalian and non-mammalian animals are summarized.

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