Hepatic B‐cell non‐Hodgkin's lymphoma of MALT type in the liver explant of a patient with chronic hepatitis C infection

Orrego, Mauricio; Guo, Li; Reeder, Craig B.; Petris, Giovanni De; Balan, Vijayan; Douglas, David D.; Byrne, Thomas; Harrison, Edwyn; Mulligan, David C.; Rodriguez-Luna, Hector; Moss, Adyr; Reddy, Kunam S.; Rakela, Jorge; Vargas, Hugo E.

doi:10.1002/lt.20384

Cited by 21 publications

(17 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The serum levels of tumor markers, including AFP, CA19-9, and CEA, were all in normal range, except for 2 cases of liver cirrhosis with slightly evaluated AFP level. [22,24] Meanwhile, distinctive radiological features were absent. Ultrasound studies showed majority of the hepatic MALT lymphomas as hypoechoic masses, [7,15,16,22,26,29,31,40,43] which was in agreement with a previous study of liver lymphomas.…”

Section: Discussionmentioning

confidence: 99%

Primary hepatic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type

Dong

Chen

et al. 2017

Medicine

View full text Add to dashboard Cite

Rationale:Primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma is an extremely rare disease. To the best of our knowledge, only 67 cases had been reported in 39 English literatures to date. The aim of this study was to add a new case of this disease to the literature and to review the current literature.Patient concerns:A 50-year-old man was incidentally identified with a solitary mass of 5 cm in diameter in the left lobe of the liver.Diagnoses:Based on the results of imaging studies, intrahepatic cholangiocellular carcinoma was suspected, and then surgery was performed. Microscopic findings showed that the tumor was a hepatic MALT lymphoma, and immunohistochemical analysis revealed that the lymphoma cells were CD20+, CD79a+, BCL-2+, CD3−, and CD5−.Interventions:The patient received rituximab after surgery.Outcomes:He was free of disease for 13 months at the time of this report.Lessons:Since previously published case reports and our case described nonspecific clinical features of this rare disease, it was usually misdiagnosed before histological confirmation and surgery resection may be a good choice for both diagnosis and local therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Primary hepatic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type

Dong

Chen

et al. 2017

Medicine

View full text Add to dashboard Cite

show abstract

“…4,18 In contrast, the incidence of hepatitis C virus (HCV) in reported cases was shown to be significantly higher in PHL than in the general population (15%-21% vs 1.1%-1.5%), 6,45 and HCV has been incriminated in the development of splenic and nodal marginal zone lymphomas, 46 as well as in MALT-type lymphomas. 26,47,48 There was no evidence of viral hepatitis in the present case. Our patient suffered from Buerger disease (ie, thromboangiitis obliterans), and it is worth mentioning that exclusion of autoimmune disease is required for diagnosis.…”

Section: Discussionmentioning

confidence: 45%

Primary Hepatic Lymphoma of Mucosa-Associated Lymphoid Tissue Type: A Case Report With Cytogenetic Study

Mahjoub¹,

Chaumette-Planckaert²,

Penas

et al. 2008

Int J Surg Pathol

View full text Add to dashboard Cite

Primary hepatic lymphoma of mucosa-associated lymphoid tissue type is extremely rare. Only 38 cases have been reported to date. A case of a 59-year-old man with Helicobacter pylori-resistant gastric ulcers and Buerger disease who was followed up since 1999 is reported. A 2-cm hepatic nodule was incidentally found during partial gastrectomy and corresponded to mucosa-associated lymphoid tissue-type lymphoma without underlying liver disease. Molecular studies showed a clonal immunoglobulin heavy-chain gene rearrangement. Investigations for the mucosa-associated lymphoid tissue lymphoma-associated translocations t(11;18) and t(14;18), as well as the t(3;14)(q27;q32), were negative, whereas trisomy 3 and trisomy 18 were detected.

show abstract

“…[8][9][10] Because both entities are rare, there have been only a few case reports, and no large series investigation has been available for either of these entities. Reviewing these case reports, they are quite similar in regarding their clinical and laboratory data and their imaging fi ndings, except for slight female predominance in PL.…”

Section: Discussionmentioning

confidence: 96%

Multinodular pseudolymphoma of the liver: computed tomography and magnetic resonance imaging findings

et al. 2011

View full text Add to dashboard Cite

A 60-year-old woman who had had a history of renal cell carcinoma with intraperitoneal recurrence presented with multiple liver masses. Computed tomography demonstrated multiple enhancing lesions in the both lobes of the liver, and there was an apparent small vessel coursing within one of the lesions. On magnetic resonance imaging, masses showed slight T1 and T2 prolongation, and restricted diffusion: On the hepatobiliary phase of liver-specific contrast agent enhancement, lesions were shown as low signal intensity of varying degree. Liver metastases from renal cell carcinoma were suspected, and partial hepatectomy was performed for the superficially located nodules to make a definitive diagnosis. The final pathological diagnosis was reactive lymphoid hyperplasia or pseudolymphoma of the liver.

show abstract

Hepatic B‐cell non‐Hodgkin's lymphoma of MALT type in the liver explant of a patient with chronic hepatitis C infection

Cited by 21 publications

References 18 publications

Primary hepatic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type

Primary hepatic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type

Primary Hepatic Lymphoma of Mucosa-Associated Lymphoid Tissue Type: A Case Report With Cytogenetic Study

Multinodular pseudolymphoma of the liver: computed tomography and magnetic resonance imaging findings

Contact Info

Product

Resources

About